DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amos and Neurog1

DIOPT Version :9

Sequence 1:	NP_477446.1	Gene:	amos / 35110	FlyBaseID:	FBgn0003270	Length:	198	Species:	Drosophila melanogaster
Sequence 2:	NP_035026.1	Gene:	Neurog1 / 18014	MGIID:	107754	Length:	244	Species:	Mus musculus

Alignment Length:	166	Identity:	54/166 - (32%)
Similarity:	68/166 - (40%)	Gaps:	33/166 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 EFSTSDSQSDGANSCSLEMYYDTPSVLELEHMLNAQEQQQHHLQANPLGKNQGRSPRYWNKQQRS 104
            |...||.....:||.|     |..|.|       ..|:....||  ||....|.|.    ..:||
Mouse     6 ETCISDLDCSSSNSSS-----DLSSFL-------TDEEDCARLQ--PLASTSGLSV----PARRS 52

  Fly   105 KPYDKLSTSMSSSTSSASSSSS------SSAGFGGEVL-----KKRRLAANARERRRMNSLNDAF 158
            .|    :.|.:|:...|.....      ..|....|.|     :.||:.||.|||.||::||.|.
Mouse    53 AP----ALSGASNVPGAQDEEQERRRRRGRARVRSEALLHSLRRSRRVKANDRERNRMHNLNAAL 113

  Fly   159 DKLRDVVPSLGHDRRLSKYETLQMAQAYIGDLVTLL 194
            |.||.|:||...|.:|:|.|||:.|..||..|...|
Mouse   114 DALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETL 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amos	NP_477446.1	HLH	137..195	CDD:238036	29/58 (50%)
Neurog1	NP_035026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		8/25 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..82		10/50 (20%)
		HLH	91..150	CDD:238036	29/59 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840