DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amos and Neurod1

DIOPT Version :9

Sequence 1:	NP_477446.1	Gene:	amos / 35110	FlyBaseID:	FBgn0003270	Length:	198	Species:	Drosophila melanogaster
Sequence 2:	NP_035024.1	Gene:	Neurod1 / 18012	MGIID:	1339708	Length:	357	Species:	Mus musculus

Alignment Length:	147	Identity:	41/147 - (27%)
Similarity:	57/147 - (38%)	Gaps:	39/147 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LGKNQGRSPRYWNKQQRSKPYDKLSTSMSSSTSSASSSSSSSAGFGGEV---------------- 135
            :|:.|.:.|..|..:..|...::...........|.::...|...|||.
Mouse    11 MGEPQPQGPPSWTDECLSSQDEEHEADKKEDELEAMNAEEDSLRNGGEEEEEDEDLEEEEEEEEE 75

  Fly   136 -----------------------LKKRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKY 177
                                   .|.||:.||||||.||:.||.|.|.||.|||.....::|||.
Mouse    76 EEDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKI 140

  Fly   178 ETLQMAQAYIGDLVTLL 194
            |||::|:.||..|..:|
Mouse   141 ETLRLAKNYIWALSEIL 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amos	NP_477446.1	HLH	137..195	CDD:238036	31/58 (53%)
Neurod1	NP_035024.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..94		10/82 (12%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		0/5 (0%)
		HLH	100..158	CDD:238036	31/58 (53%)
		Neuro_bHLH	160..284	CDD:289310
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2611
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.870