Protein Alignment amos and Atoh1

DIOPT Version :9

• Sequence 1: NP_477446.1
• Gene: amos / 35110
• FlyBaseID: FBgn0003270
• Length: 198
• Species: Drosophila melanogaster
• Sequence 2: NP_031526.1
• Gene: Atoh1 / 11921
• MGIID: 104654
• Length: 351
• Species: Mus musculus
• Alignment Length: 208
• Identity: 72/208 - (34%)
• Similarity: 95/208 - (45%)
• Gaps: 47/208 - (22%)

  Fly    12 YFPDEAPAIPEFLSNDTFQQLEQLMYQQEFSTSDSQSDGANSCSLEMYYDTPSVLELEHMLNAQE 76
            :.|...|..|.     |.|..:..:|..|.|..||....|        :.||:   |:.:..|:
Mouse    27 HVPPLTPQPPA-----TLQARDLPVYPAELSLLDSTDPRA--------WLTPT---LQGLCTAR- 74

  Fly    77 QQQHHLQANPLGKNQGRSPRYWNKQQ----RSKPYDKLSTS---------------------MSS 116
            ..|:.|.:..||.::..:||.....|    |......||.|                     :..
Mouse    75 AAQYLLHSPELGASEAAAPRDEADSQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGC 139

  Fly   117 STSSASSSSSSSAGFGGEVLKKRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKYETLQ 181
            |...|.||...:.     |.|:|||||||||||||:.||.|||:||:|:||..:|::||||||||
Mouse   140 SRQRAPSSKQVNG-----VQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQ 199

  Fly   182 MAQAYIGDLVTLL 194
            |||.||..|..||
Mouse   200 MAQIYINALSELL 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amos	NP_477446.1	HLH	137..195	CDD:238036	41/58 (71%)
Atoh1	NP_031526.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..39		3/16 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..116		6/26 (23%)
		HLH	155..213	CDD:238036	41/58 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..278
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	308..351

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835486
Domainoid	1	1.000	79	1.000	Domainoid score	I8704
eggNOG	1	0.900	-	-		E1_KOG4395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto93063
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19290
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2611
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.870