DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15160 and cids-1

DIOPT Version :9

Sequence 1:	NP_001286047.1	Gene:	CG15160 / 35109	FlyBaseID:	FBgn0032688	Length:	834	Species:	Drosophila melanogaster
Sequence 2:	NP_498807.2	Gene:	cids-1 / 176162	WormBaseID:	WBGene00015347	Length:	315	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	78/320 - (24%)
Similarity:	137/320 - (42%)	Gaps:	54/320 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FDEELFETRLEALKDTQEGIQQMSNWCLQHRSNHKKIIQCWLNVFKRVRVDHRLV-LFYLANDVI 68
            |.|:....:|..|.:....||..|.|.||:.||.:.||:.||...|:.....::| |.|:||||.
Worm     4 FTEQTLRQKLTNLSNHPSSIQTTSAWLLQNHSNRELIIRVWLKTVKKETHGSKIVNLLYVANDVS 68

  Fly    69 QYSKRK----RYEFVECWATALQRATTMVRDERVKDKILRIFKIWEQREIYNEEYLSDLSGLLNI 129
            |.:::.    :.||.....::.:.|..:...:.|:..|.::..:|:.|:|:.......|..:
Worm    69 QNARKTCPQFKDEFFPAIESSFRHAIELKNAKEVEHAIGKLINVWKDRQIFTPSQCKRLHEV--- 130

  Fly   130 APPKKSQVDVSDEFQNATL-------IAQ-----VRECVELAEITDKSMQKLPKPPTFEIEVIK- 181
                ..||.:|..|....:       :||     |.|..:.|:....|:::|..||:.|.|:..
Worm   131 ----HQQVKLSGSFPTPAVANKEHGKVAQPSQFVVEEAKKNAQDVLLSLKRLQNPPSTEREIRTE 191

  Fly   182 --------------QQLKDKSHSGNIEKEVERCVAFINAYNKNLQNEIKSRKAVLAS----IEAA 228
                          |.::....:.::..:.|..:..:..|.|.|:||...|:.:.::    ||..
Worm   192 LSKYPDNISCPEKLQSVRSSQEAQSLLVQNEEALPMLEEYVKRLKNETNERETLESNLNMLIENV 256

  Fly   229 KKFYEHQGKEVKVVASAYKSFGTRIK---IVKRKLDETIPNLASPIPSPDVNAPSPERDA 285
            :...||..|..:.|    |....|||   :...|..|::|:||:.:|    |||.|..:|
Worm   257 RMSIEHHEKLCREV----KRREDRIKADLLEVEKTFESLPDLAAEMP----NAPLPTLEA 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15160	NP_001286047.1	RPR	10..128	CDD:214731	32/122 (26%)
cids-1	NP_498807.2	RPR	8..132	CDD:214731	32/130 (25%)
cids-1	NP_498807.2	CREPT	169..310	CDD:293174	35/148 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2669
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091009at2759
OrthoFinder	1	1.000	-	-		FOG0000693
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12460
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1901
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950