Protein Alignment CG15160 and cids-2

DIOPT Version :10

• Sequence 1: NP_001286047.1
• Gene: CG15160 / 35109
• FlyBaseID: FBgn0032688
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_001122472.1
• Gene: cids-2 / 172691
• WormBaseID: WBGene00009451
• Length: 664
• Species: Caenorhabditis elegans
• Alignment Length: 786
• Identity: 168/786 - (21%)
• Similarity: 267/786 - (33%)
• Gaps: 209/786 - (26%)

  Fly    20 TQEGIQQMSNWCLQHRSNHK--KIIQCWLNVFKRVRVDH-RLVLFYLANDVIQYSKRKRYE-FVE 80
            |||.|:.||.|.:.::.|..  .|:..|||.||....|: |:.|||:.|||:|.:|.|..: .:.
 Worm    22 TQEAIETMSMWIMHYKDNASIDLIVDGWLNCFKTAGTDNKRIALFYVMNDVVQKAKMKHADTLIP 86

  Fly    81 CWATALQRATTMVR-DERVKDKILRIFKIWEQREIYNEEYLSDLSGLLNI-------APPKKSQV 137
            .:..|:..|..:.| .::||..:.|..:|::.|.:::....:.:..||..       |..:..:|
 Worm    87 AFQPAVLTAVGIGRKQDKVKAVMKRCIQIFKSRNVFSPASTTAMENLLASDADEGYEAEDQALEV 151

  Fly   138 DVSDEFQNATLIAQVRECVELAEITDKSMQKLPKPPTFEI-EVIKQQLKDKSHSGNIEKEVERCV 201
            |..|..:..|.....|..|       ..|.|......|:. |:.|..::|:...|:|..||...:
 Worm   152 DSDDLVKKITNFISARNVV-------ADMMKCVNEGNFDYKEMCKHGMRDREEGGHILHEVHEAI 209

  Fly   202 AFINAYNKNLQNEIKSRKAVLASIEAAKKFYEHQGKEVKVVASAYKSFGTRIKIVKRKL-----D 261
            ..:.....:::::.|...|:..::|.||:.:.||.:||.||..||.:|...||.|..:|     .
 Worm   210 DTMVQVRHSMEDQKKKMMALSETLELAKRVFLHQKREVLVVEEAYVNFRDGIKAVHTELLDMEAK 274

  Fly   262 ETIPNLASPIPSPDVNAPSPERDADLQLPEENNIPLNLFGGSINGFTSYLDGGKLPFDINDFKRD 326
            :..|.|.||                     .|......:|.|.|...|...|
 Worm   275 KVYPGLLSP---------------------RNEDDRQTYGRSNNRSLSQQWG------------- 305

  Fly   327 SKDRGSAIEVIGSRSDDEAYVPSANFYKPEPISSADSSSIPGLGGSAVYTPDAPLFGSNSQDQYV 391
              |..:.|::  ...:||.  |.|...||...:....:|.|.| .|.:.........:..::.:.
 Worm   306 --DNRNQIDM--EMDEDER--PQAPMMKPSLQALVGIASQPSL-QSRIMQLGLKKIANGDEEMFQ 363

  Fly   392 PPPPSHLYGDNGNGGSSGGPSDQYTPAPMPPPPLPPSLGPSSGSADDFNSTWNMSMSWTPLDSSL 456
            |              ::...:|...|:...|||..|::                          :
 Worm   364 P--------------TTTTTADTPLPSTFQPPPSKPAV--------------------------I 388

  Fly   457 NSSGASSSSYANQSTPNSPPHFDRKASSTAAPIEYNELL--HTNPAALGAEDVDHRTLQLPPAFE 519
            |:|..|....|..|.|.|.|   |..|....|.:|...|  |..|...|.:.|.:| :..||..:
 Worm   389 NASKFSMPPPAITSAPLSDP---RIRSDGEGPSQYAIALKQHGLPPPTGQQPVQNR-MNAPPPAQ 449

  Fly   520 FGAKLGLSKDKSRQLVDIDHRNLISLTGSPGGAEKDFTGGDVDYRIVPSPNDEGI---MAPPGNN 581
            ......:.:....|.|         ..|..|||.        |.|:..|...:.:   ..||...
 Worm   450 PSPYQAIPQKPVEQTV---------YQGQFGGAR--------DPRLANSVTPQSVAVAQQPPITG 497

  Fly   582 YAKSKTCSPLKSNASSSSESDRVDGATRYDPADMVIDMDMSDDDIDESLREPKEDNGDAEIDANG 646
            |                        ..:|                 |.:|:|:       |....
 Worm   498 Y------------------------QAQY-----------------EQIRDPR-------ILQQA 514

  Fly   647 ALTPSRPVLLET-PPDFINPWDANNSF--------MGPPLPDEEDQQQHHEQQQNQQQELQQHHQ 702
            |.........|. .|..::|...||.:        :.|.:|..:...|:|:|:....|...||||
 Worm   515 APQQGYQATFEVQKPQLVSPQIQNNGYQARFEQSQLSPSIPQHQPVGQYHQQKNTYCQPPPQHHQ 579

  Fly   703 HQQHQQQ-----QPWNQMNRMQMGGGGAPPPPRPPYGQPFPPFQRFPGPPMNGPDGMQRGRGRGR 762
            :||..||     ..::..:|....|       |..|.......:|....|.|..        ||.
 Worm   580 YQQQSQQSHGYSSDYHSGDRRDDRG-------RDNYQNSRYDDRRGSSAPYNNQ--------RGD 629

  Fly   763 GWNGPG 768
            .|.|.|
 Worm   630 RWRGSG 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15160	NP_001286047.1	CID_RPRD_like	7..127	CDD:340778	33/111 (30%)
cids-2	NP_001122472.1	RPR	20..134	CDD:214731	33/111 (30%)
		PHA03247	<375..559	CDD:223021	50/278 (18%)