Protein Alignment Pde11 and Pde7a

DIOPT Version :10

• Sequence 1: NP_609885.2
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_112342.1
• Gene: Pde7a / 81744
• RGDID: 68391
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 88/334 - (26%)
• Similarity: 158/334 - (47%)
• Gaps: 37/334 - (11%)

  Fly   803 RLHDFKFDDIHFE----DDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVT-YHNW 862
            ::.::.||...|:    .:..:.....:|.....:|.||:|...|.|:|:.::::|.:.. |||.
  Rat   150 KVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNA 214

  Fly   863 RHAFNVAQMMFAIL-------TTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLA 920
            .||.:|.|.|...|       :.|.|       :.|..:|....|||||.|.|..|.||.:..||
  Rat   215 VHAADVTQAMHCYLKEPKLANSVTPW-------DILLSLIAAATHDLDHPGVNQPFLIKTNHYLA 272

  Fly   921 QLY-STSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLE 984
            .|| :||.:|:||:...:.:|...|  :.::|..:....:...:...||:||::...:....|..
  Rat   273 TLYKNTSVLENHHWRSAVGLLRESG--LFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRS 335

  Fly   985 SVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQ-ELNITP 1048
            .:.:...:......|.|:..|::...|:....:.||:.|:.::.|:.|||.|||:||: .|.::|
  Rat   336 HLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSP 400

  Fly  1049 IDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSD-KLEPLVEG-VRDNRGHWIDLADVVKTKT 1111
              :.:|:.| .:..:|:.|:..:..|::..:|..|| :|...:.| |..|:..|         |.
  Rat   401 --LCDRQTE-SIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASW---------KG 453

  Fly  1112 SQDQEPEEE 1120
            .|.|:|..|
  Rat   454 LQRQQPSSE 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_609885.2	GAF	420..582	CDD:214500
		GAF	611..762	CDD:214500
		PDEase_I	859..1093	CDD:459723	68/244 (28%)
Pde7a	NP_112342.1	PDEase_I	211..431	CDD:459723	64/231 (28%)