Protein Alignment Pde11 and pde9ab

DIOPT Version :10

• Sequence 1: NP_609885.2
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: XP_700447.6
• Gene: pde9ab / 571737
• ZFINID: ZDB-GENE-210629-1
• Length: 518
• Species: Danio rerio
• Alignment Length: 602
• Identity: 153/602 - (25%)
• Similarity: 258/602 - (42%)
• Gaps: 138/602 - (22%)

  Fly   553 FSEIDEKV----FSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIE------- 606
            :.::|.||    ||.:...|.|  |:...   |...|.||..:|    :|..|.:.|.
Zfish    14 YLDVDGKVQRVIFSRHCSPCDI--RDLLC---SSSNIARNTAVL----LIDSEGALISIDPTMPA 69

  Fly   607 ---HMVFRILTHM--QSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSPYESRFP 666
               :.:::::.|.  |...:....|.:|...|::  |:|.|   .|...:.|.|:|.:..|.|..
Zfish    70 NTPNNLYKVMPHSTNQGEEKEDMFQNVLSQVAEQ--FTRAF---RNSELKTEVTNRLAMLEKRVE 129

  Fly   667 INIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFN 731
            :            |.:.|            |:...|           ||.|.::
Zfish   130 L------------EGLKV------------VEIEKC-----------KNDLKKL----------- 148

  Fly   732 ELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRV 796
                  .||....:..:.|....:.|...:|.       |...:|.:|.......|.  :..|:.
Zfish   149 ------KDEMTSGSMRVNCNCKYNFTDDGKKL-------SPRRDVPNYPKYTLSQET--IDALKK 198

  Fly   797 PSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHN 861
            |:          ||..|:|.::.|.....|:.||..|:.|:::...|.||||::::|||:..:||
Zfish   199 PT----------FDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRDNPFHN 253

  Fly   862 WRHAFNVAQMMFAI---------LTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASS 917
            :||.|.|:|||:.:         ||.|..        |: |:...:||||||.|.||::||.|.:
Zfish   254 FRHCFCVSQMMYGMIHLCGLQDRLTMTDM--------CI-LMTAAVCHDLDHPGYNNTYQINART 309

  Fly   918 PLAQLYS-TSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGP 981
            .||..|: .|.:|:||......||:.|...|.||:..:.:.::.:.:...||:||:|    |.|.
Zfish   310 ELAVRYNDISPLENHHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMA----KHGE 370

  Fly   982 FLESVSQPTSYW--VAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQE- 1043
            .|:|..|....:  ..||....|:.:.:..||:|...:|.|:.:...|.:..|:|.|.|.||.|
Zfish   371 ILDSFKQKVDNFDCTNEEHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEG 435

  Fly  1044 LNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEP-LVEGVRDNRGHWIDLADVV 1107
            |.:.|  .|:|:|..: |..|:.||..:.:|::|....|..::|. :|:.:||:|.|:.:|..:
Zfish   436 LPVAP--FMDRDKVTK-PTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQI- 496

  Fly  1108 KTKTSQDQEPEEEQQQQ 1124
                  |....|.|:::
Zfish   497 ------DDAMSEAQKKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_609885.2	GAF	420..582	CDD:214500	8/32 (25%)
		GAF	611..762	CDD:214500	25/152 (16%)
		PDEase_I	859..1093	CDD:459723	79/247 (32%)
pde9ab	XP_700447.6	None