Protein Alignment Pde11 and pde4ca

DIOPT Version :9

• Sequence 1: NP_001286044.1
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: XP_009296827.1
• Gene: pde4ca / 565259
• ZFINID: ZDB-GENE-070912-373
• Length: 742
• Species: Danio rerio
• Alignment Length: 404
• Identity: 103/404 - (25%)
• Similarity: 185/404 - (45%)
• Gaps: 45/404 - (11%)

  Fly   827 FLDLDFVERFHIDYEVLCRWLLSVKKNYR-NVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIEC 890
            |.:.|.::.|.|..:....::.::::||| :|.|||..||.:|.|....:|:|.....:|.::|.
Zfish   340 FQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEI 404

  Fly   891 LALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYS-TSTMEHHHFDQCLMILNSPGNQILANLSSD 954
            ||.:.....||:||.|.:|.|.|..:|.||.:|: :|.:|:||......:|......|..||:..
Zfish   405 LAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKK 469

  Fly   955 DYCRVIRVLEDAILSTDLAVYFKKRGPF--LESVSQPTSYWV------AEEPRALLRAMSMTVC- 1010
            ....:.:::.|.:|:||::.:.......  :....:.||..|      ::..:.|   .:|..|
Zfish   470 QRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVL---QNMVHCA 531

  Fly  1011 DLSAITKPWEIEKRVADLVSSEFFEQGDMEKQE-LNITPI-DIMNREKEDELPMMQVNFIDSICL 1073
            |||..|||.|:.::..|.:..|||.|||.|:.: :.|:|: |..|...|..    ||.|||.|..
Zfish   532 DLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKS----QVGFIDYIVH 592

  Fly  1074 PIYEAFATL-SDKLEPLVEGVRDNRGHWIDLADVVKTKTSQDQEPEEEQQQQNVISNGDCKAMSD 1137
            |::|.:|.| ....:.:::.:.|||..:..:.....|.|     ||::.....:.:.|...|.:.
Zfish   593 PLWETWADLVHPDAQEILDTLEDNREWYQSMIPHSPTST-----PEDKSAVMGMGAMGGGIASAG 652

  Fly  1138 DD-----VAASEAEVAVDSPSEKASVNGSNVANNSSNTNKKIAVASHPTSTQ------------- 1184
            |.     ....|.|..|:||.::...:.:..::.:....|:.:.|:...|.:
Zfish   653 DKFQFELTLEEEGESDVESPVDEDLTSSTRDSSRTDPQGKQTSPAARLLSARSPGCRTMSFKMGE 717

  Fly  1185 -PSDDDNDVDADAD 1197
             |..:|.|.:.|.:
Zfish   718 PPDSEDEDKELDQE 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_001286044.1	GAF	420..582	CDD:214500
		GAF	611..762	CDD:214500
		PDEase_I	859..1094	CDD:278654	73/247 (30%)
pde4ca	XP_009296827.1	PDEase_I	373..610	CDD:306695	73/243 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750