Protein Alignment Pde11 and pde1a

DIOPT Version :9

• Sequence 1: NP_001286044.1
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: XP_005167982.1
• Gene: pde1a / 564465
• ZFINID: ZDB-GENE-090831-2
• Length: 611
• Species: Danio rerio
• Alignment Length: 596
• Identity: 141/596 - (23%)
• Similarity: 248/596 - (41%)
• Gaps: 99/596 - (16%)

  Fly   714 KNSLGQIIGVIQLINK--FNELDFTKNDENFVEAFAIFCGMGIHNTHMY---EKAIVAMAKQSVT 773
            ||:..::..:::.::|  .|.:|..||.|   .|.::...:.|..|...   |..:..:...||.
Zfish    37 KNTSQRLRCLVKQLDKGEVNVVDLRKNIE---YAASVLEAVYIDETRRLLDTEDELSDIQADSVP 98

  Fly   774 LEVLSYHASATMDEAHRLRR---------------------------------LRVPSAVHFRLH 805
            :||..:.||....:...:||                                 |..|.:|...|.
Zfish    99 MEVRDWLASTFTRKMGVVRRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMAGLTYPPSVITALK 163

  Fly   806 D---FKFDDIHFED---DDTLKACL-RMFLDLDFVERFHIDYEVLCRWLLSVKKNY---RNVTYH 860
            |   :.||....::   |..||..: .:....|.:.||.|....|..::.:::..|   || .||
Zfish   164 DVDKWSFDVFKLQEASSDHALKFLVYELLTRYDLISRFRIPVSSLVSFVEALEIGYSKHRN-PYH 227

  Fly   861 NWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYS- 924
            |..||.:|.|....::..|.......|:|.||::.....||.:|.||.|:|.|:..|.:|.||:
Zfish   228 NLIHAADVTQTAHYLMLHTGVMHWLTELEILAMVFAAAIHDFEHTGTTNNFHIQTRSEVAILYND 292

  Fly   925 TSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQP 989
            .|.:|:||......::......||.|||.||:..:..::.:.::|||::.:|::......|:.||
Zfish   293 RSVLENHHVSAAYRLMQEDEMNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQQIKTMRNSLQQP 357

  Fly   990 TSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNR 1054
            ..   .::.:||  ::.:...|:|...|.|::..|....:..|||.|||.| .||.: |...:..
Zfish   358 EG---IDKAKAL--SLMLHAADISHPAKGWKLHYRWTQALMEEFFRQGDKE-AELGL-PFSPLCD 415

  Fly  1055 EKEDELPMMQVNFIDSICLPIYEAFATLSDK-LEPLVE------GVR----DNRGHWIDLADVVK 1108
            .|...:...|:.|||.|..|.:......::| :.||:|      |||    ..||.    |.||
Zfish   416 RKATMIAQSQIGFIDFIVEPTFSVLVDTTEKIISPLIEEAVKSGGVRRSSLTGRGS----AAVV- 475

  Fly  1109 TKTSQDQEPEEEQQQQNVISNGDCKAMSDDDVAASEAEVAVDSPSEKASVNGSNVANNSSNTNKK 1173
                     |..|:..:..||.:|...:|..:.      .:|....:..:  |.:..|:....|:
Zfish   476 ---------ESVQRHSDRGSNDECGGSTDYSLC------GIDQKHVRHLL--SEIIQNNKERWKE 523

  Fly  1174 IAVASHPTSTQPSDDDNDVDADADDVDEQAAEENGHDAE---VDEASCRSNSTCSSSTASSCLST 1235
            ::|  ...:.:..:..:|:..:.....:....:..||:|   ::|.: .::||.||..:....|.
Zfish   524 LSV--QELANKQHERMSDLQEEPMRSTQLTLSQENHDSESKSLNELN-NTDSTHSSQDSLDQSSQ 585

  Fly  1236 PPPTGEDDSTP 1246
            .|..|..|::|
Zfish   586 SPTEGAGDASP 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_001286044.1	GAF	420..582	CDD:214500
		GAF	611..762	CDD:214500	11/52 (21%)
		PDEase_I	859..1094	CDD:278654	71/242 (29%)
pde1a	XP_005167982.1	PDEase_I_N	85..141	CDD:285672	9/55 (16%)
		PDEase_I	226..442	CDD:278654	66/222 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920