Protein Alignment Pde11 and pde9ac

DIOPT Version :9

• Sequence 1: NP_001286044.1
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: XP_692819.3
• Gene: pde9ac / 564389
• ZFINID: ZDB-GENE-130530-807
• Length: 558
• Species: Danio rerio
• Alignment Length: 576
• Identity: 151/576 - (26%)
• Similarity: 251/576 - (43%)
• Gaps: 112/576 - (19%)

  Fly   624 RVQI-LLVHEADKGSFSRVFD-----FEANDLSEEEATSR-TSPYE--------SRFPINIGI-- 671
            |||: |.||..:.||.|..:.     .:.:...::...|| .||.:        |..|.|..|
Zfish    28 RVQVDLTVHFINMGSASSSYSPKTIYLDVDGKVQKVLFSRHCSPCDIKELLCSSSNIPRNTAIMM 92

  Fly   672 ---TGHVATTGETV--NVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFN 731
               .|.:.:...|:  |.||                |.::.|...|  :.||:...:.|.:
Zfish    93 TDPEGAIVSIDPTMPTNNPN----------------FLYKIIPLSA--SQLGEKEDMFQNV---- 135

  Fly   732 ELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVL------------------- 777
               .::..|.|..||.|    ....|.:..:  :||.::.|.||.|
Zfish   136 ---LSQVAEQFSRAFRI----NELKTEVTNR--LAMLEKRVELEGLKVVEIEKCKNDMRKLRDEM 191

  Fly   778 ------------SYHASATMDEAHRLR-RLRVPSAVHFRLHDF--------KFDDIHFEDDDTLK 821
                        .|:.|   |:..:|. |..:||...:.|...        .||..|:|.::.|.
Zfish   192 TSRAGARVNCPCKYNFS---DDGKKLTPRRDIPSYPKYTLSQETIEALKKPTFDVWHWEHNEMLS 253

  Fly   822 ACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFG 886
            ....|:.||..|:.|:|:...|.||||.:::|||:..:||:||.|.|:|||:.::......:...
Zfish   254 CLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRSNPFHNFRHCFCVSQMMYGMIHLCNLQEKLT 318

  Fly   887 EIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYS-TSTMEHHHFDQCLMILNSPGNQILAN 950
            ..:...|:...:||||||.|.||::||.|.:.||..|: .|.:|:||......||:.|...|.||
Zfish   319 LTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFAN 383

  Fly   951 LSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSY--WVAEEPRALLRAMSMTVCDLS 1013
            :..:.:.::.:.:...||:||:|    :.|..|:|......:  :..||..|.|:.:.:..||:|
Zfish   384 VEPEAFKQIRQAIITLILATDMA----RHGEILDSFKHKVDHFDFTNEEHVACLKMVLIKCCDIS 444

  Fly  1014 AITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEA 1078
            ...:|.|:.:...|.:..|:|.|.|.||.| .:.....|:|||..: |..|:.||..:.:|::|.
Zfish   445 NEVRPTEVAEPWVDCLLEEYFMQSDREKSE-GLPVAAFMDREKVTK-PTAQIGFIKFVLIPMFET 507

  Fly  1079 FATLSDKLEP-LVEGVRDNRGHWIDLADVVKTKTSQDQEPEEEQQQQNVISNGDCK 1133
            ...|..::|. :|:.:||:|.|:.:|      |...|...|.::::...:|.|..|
Zfish   508 VMKLFPQIEEIMVQPLRDSRDHYEEL------KQIDDAMTEAQKKKTESLSLGGKK 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_001286044.1	GAF	420..582	CDD:214500
		GAF	611..762	CDD:214500	34/159 (21%)
		PDEase_I	859..1094	CDD:278654	73/238 (31%)
pde9ac	XP_692819.3	PDEase_I	291..521	CDD:278654	72/235 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820