DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pde11 and pde7a

DIOPT Version :9

Sequence 1:	NP_001286044.1	Gene:	Pde11 / 35107	FlyBaseID:	FBgn0085370	Length:	1451	Species:	Drosophila melanogaster
Sequence 2:	XP_031760262.1	Gene:	pde7a / 100498541	XenbaseID:	XB-GENE-1013813	Length:	480	Species:	Xenopus tropicalis

Alignment Length:	303	Identity:	85/303 - (28%)
Similarity:	152/303 - (50%)	Gaps:	38/303 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   833 VERFHIDYEVLCRWLLSVKKNYRNVT-YHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIG 896
            ::.|.:|...|.|:|:.|:::|.:.. |||..||.:|.|.|:..|...:..|.|...:.|..:|.
Frog   199 IDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIA 263

  Fly   897 CLCHDLDHRGTNNSFQIKASSPLAQLY-STSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVI 960
            ...|||||.|.|.||.||.:..||.|| :||.:|:||:...:.:|...|  :.|:::.::...:.
Frog   264 AATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESG--LFAHMTLEERQHME 326

  Fly   961 RVLEDAILSTDLA---VYFKK------RGPF-LESVSQPTSYWVAEEPRALLRAMSMTVCDLSAI 1015
            ..|...||:||::   .|..:      ||.. |::.|.          |..:..|::...|:...
Frog   327 GQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNASD----------RLFILQMALKCADICNP 381

  Fly  1016 TKPWEIEKRVADLVSSEFFEQGDME-KQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAF 1079
            .:.||:.|:.::.|:.|||.|||:| |.:|:::|  :.:|:..: :..:|:.||..:..|::..:
Frog   382 CRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSP--LCDRQTSN-IANIQIGFITYLVEPLFVEW 443

  Fly  1080 ATLSD-KLEPLVEG-VRDNRGHWIDLADVVKTKTSQDQEPEEE 1120
            |..|: :|...:.| |..|:..|..:.        |::...||
Frog   444 ARFSNTRLSQTMLGHVGLNKASWKGML--------QERSSSEE 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_001286044.1	GAF	420..582	CDD:214500
		GAF	611..762	CDD:214500
		PDEase_I	859..1094	CDD:278654	72/248 (29%)
pde7a	XP_031760262.1	PDEase_I	226..459	CDD:395177	72/247 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010