Protein Alignment Pde11 and pde11a

DIOPT Version :9

• Sequence 1: NP_001286044.1
• Gene: Pde11 / 35107
• FlyBaseID: FBgn0085370
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: XP_002934646.1
• Gene: pde11a / 100379882
• XenbaseID: XB-GENE-5999893
• Length: 892
• Species: Xenopus tropicalis
• Alignment Length: 942
• Identity: 383/942 - (40%)
• Similarity: 541/942 - (57%)
• Gaps: 118/942 - (12%)

  Fly   195 EHARMEAWLDENQEFVQDYFIRKATRQTVDAWLVSHATSAGNDVVSSTSPTHANGQTSS--SRGG 257
            :.:::|.:||.:.|..:||.|||...|.|:.|:      ..|.:..:.|.:.|:.::..  |..|
 Frog     7 DFSKVERYLDNHPELFEDYLIRKGKHQMVERWM------KRNQLAKTPSSSSADDKSKDCWSNRG 65

  Fly   258 SGATTPVRKISAHEFERGGLLKPIVNTIDGTPTFLSIGPPMDNGSVGGSCSNLQNVGGVVAGQYQ 322
            .|..   |:.|..|..:.......:|.
 Frog    66 DGLQ---RRASQKELRKSFARSKAINV-------------------------------------- 89

  Fly   323 YNHQQHHHNHAHLHHSQHSHYQAGGAVGSSSLGSTGGASGAGGAPSLGGSGGAGNGH-------- 379
             |.....|.::.......|..:......:|||..|                   ..|
 Frog    90 -NRTYDEHVNSRAQEPLTSMRRRALLRKASSLPPT-------------------TAHILSALLES 134

  Fly   380 -----QYP-------YYHCHQRPQRLSRNELKQLDEKELIFELVKDICNELEVRTLCHKILQNVS 432
                 |||       ||             ||:.:|:....||||||.|||.:.:||:|||..|.
 Frog   135 RVNIPQYPSTAIDYIYY-------------LKEHNERAFFLELVKDISNELNLTSLCYKILIFVC 186

  Fly   433 ILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVE---EMEQQDEVRVAWGTGIAGHVA 494
            |:::|||.|||||:|..|     ||.||||.|||...:|:.   ..|..:||:|.||.||.|:||
 Frog   187 IMVDADRCSLFLVEGTAN-----KKSLVSKFFDVHAGTTLLPSCSTENSNEVQVPWGKGIIGYVA 246

  Fly   495 ESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKM-NGECFSEIDE 558
            |.||.|||||||||.||:.|||.||||:||:||||||:.|.|::|||||.|||. .|..|.|.||
 Frog   247 EHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKTPGGAPFIEDDE 311

  Fly   559 KVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQ 623
            ||...||.||||.:.||||:..|:.|..|::.||::...:||||:.:|.:|.:|:...|:|::|:
 Frog   312 KVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKVVKKIMHRAQNLLKCE 376

  Fly   624 RVQILLVHEADKG--SFSRVFDFEANDLSEEEATSRTSPYE----SRFPINIGITGHVATTGETV 682
            |..:||:.:.:..  .|::.|:..:...|.:...|.....|    |.:.:|..|...||:||..|
 Frog   377 RCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSVEKSSYSDWLVNNSIAELVASTGLPV 441

  Fly   683 NVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFA 747
            |:.:||:|.|||...|:.|.|..||:||:.|.||..|||||.|::|:.:...|...|:...|||.
 Frog   442 NISDAYQDPRFDVEADQFSGFHIRSVLCVPIWNSSHQIIGVAQVLNRIDGKPFDDADQRLFEAFV 506

  Fly   748 IFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDI 812
            ||||:||:||.||::...:.|||||.|:||||||:.:..|..:.:...:|......:.|..|||.
 Frog   507 IFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELSIADIHFDDF 571

  Fly   813 HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILT 877
            ..:.|..:.|.||||::|..|::|.||||.||||||:::||||.|.||||||||||.|:|||:||
 Frog   572 CLDVDAMISAALRMFMELGMVQKFKIDYETLCRWLLTIRKNYRMVLYHNWRHAFNVCQLMFAMLT 636

  Fly   878 TTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYSTS-TMEHHHFDQCLMILN 941
            |..:.::..:.|.||||:||||||||||||||:||.|:.|.|:|||.|| |:|||||:..:|||.
 Frog   637 TAGFQEVLSDTETLALIVGCLCHDLDHRGTNNAFQAKSGSALSQLYGTSATLEHHHFNHAVMILQ 701

  Fly   942 SPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMS 1006
            |.|:.|.|||||.:|..::::|:.:||:||:.::|::|..|.|.|::....|..:..|.:.|:|.
 Frog   702 SEGHNIFANLSSQEYSDLMQLLKQSILATDITLHFERRNEFFELVNKGDYNWNVKSHRVIFRSML 766

  Fly  1007 MTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSI 1071
            ||.|||.|.||||||.::||:||:||||||||.|:.||.:||..|.:|.::||||.:|:.:||:|
 Frog   767 MTACDLGAATKPWEISRQVAELVTSEFFEQGDRERLELKMTPSAIFDRNRKDELPRLQLEWIDNI 831

  Fly  1072 CLPIYEAFATLSDKLEPLVEGVRDNRGHWIDL 1103
            |.|:||:...::.||:|:::.|..|||.|.:|
 Frog   832 CFPLYESLVKINGKLKPMLDSVTTNRGKWEEL 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde11	NP_001286044.1	GAF	420..582	CDD:214500	94/165 (57%)
		GAF	611..762	CDD:214500	59/156 (38%)
		PDEase_I	859..1094	CDD:278654	124/235 (53%)
pde11a	XP_002934646.1	GAF	173..335	CDD:214500	94/166 (57%)
		GAF	357..523	CDD:214500	61/165 (37%)
		PDEase_I	618..853	CDD:365964	124/234 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D114875at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010