Protein Alignment CG10211 and PTGS2

DIOPT Version :9

• Sequence 1: NP_001286043.1
• Gene: CG10211 / 35106
• FlyBaseID: FBgn0032685
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: NP_000954.1
• Gene: PTGS2 / 5743
• HGNCID: 9605
• Length: 604
• Species: Homo sapiens
• Alignment Length: 581
• Identity: 124/581 - (21%)
• Similarity: 205/581 - (35%)
• Gaps: 160/581 - (27%)

  Fly   716 NSPF-------RTLSGRCNNLRNP----------NWG--KSLTTFSRLLPAQYEDGISAPRLTGV 761
            |.||       ..|:.|.:.:.:|          :|.  .:|:.::|.||...:|   .|...||
Human    90 NIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDD---CPTPLGV 151

  Fly   762 TG-TALPNPRTISTTI--------HPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPS 817
            .| ..||:...|...:        .|..||      :|...|||...|....|...:|
Human   152 KGKKQLPDSNEIVEKLLLRRKFIPDPQGSN------MMFAFFAQHFTHQFFKTDHKRG------- 203

  Fly   818 CRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPGQQSLGPRDQINQNTHFLD 882
                               ||         .|:|                ||         |.:|
Human   204 -------------------PA---------FTNG----------------LG---------HGVD 215

  Fly   883 GSMVYGETTCLSNKLRGFSGRMNSTQVRGKELLPLGPHPECKSRNG-----------LCFLGGDD 936
            .:.:||||.....|||.|.......|:...|:.|    |..|....           |.|..|.:
Human   216 LNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYP----PTVKDTQAEMIYPPQVPEHLRFAVGQE 276

  Fly   937 RASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSW 1001
            .....|||....|.:||||||:.:.|:..:|.|..||||..:|.|:..:...||..:::..:..:
Human   277 VFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGY 341

  Fly  1002 NAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIG---HSLLRPHIPRLSVQHQPVEPPLL 1063
            :    :.||..|:            ::||:......||.   ::|...| |.|....|..:....
Human   342 H----FKLKFDPE------------LLFNKQFQYQNRIAAEFNTLYHWH-PLLPDTFQIHDQKYN 389

  Fly  1064 LRDGFFRMDALLQPGIIDEILRGLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRA 1128
            .:...:....||:.||...:         |:..:.|.|.|..    .|.:|.:...:...:|.::
Human   390 YQQFIYNNSILLEHGITQFV---------ESFTRQIAGRVAG----GRNVPPAVQKVSQASIDQS 441

  Fly  1129 RDHGIPSYNNYRALCNLKRATNWNDLSREIPTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLV 1193
            |.....|:|.||....||...::.:|:.|  .|:....:.:|..:|.::|:|..:.|:|....:.
Human   442 RQMKYQSFNEYRKRFMLKPYESFEELTGE--KEMSAELEALYGDIDAVELYPALLVEKPRPDAIF 504

  Fly  1194 GPTLACIIGIQFRQLRK------CD-RFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLE 1247
            |.|:. .:|..| .|:.      |. .:|    .|.....|.....:...::..::|.|::
Human   505 GETMV-EVGAPF-SLKGLMGNVICSPAYW----KPSTFGGEVGFQIINTASIQSLICNNVK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	121/574 (21%)
		peroxinectin_like	871..1245	CDD:188655	88/394 (22%)
PTGS2	NP_000954.1	EGF_CA	19..54	CDD:238011
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	124/581 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810