DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10211 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	866	Identity:	154/866 - (17%)
Similarity:	276/866 - (31%)	Gaps:	275/866 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 EGELRHAHITA-MLPAWGQLLANDLVEVGQLPISGKCCERDSAVKDPSELQHCFVRAGPDCKEYK 193
            :|.:|.|.:|. .|..:..:..|.|..:||.|      .....:|||....   ||.|   .||:
Zfish   379 DGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSP------PATLVLKDPPYFN---VRPG---GEYR 431

  Fly   194 RSAPGFDLEACQKHTRQQMNIASAYIDGSGLYGSTRHEFDQLRTYISGGVKVESCKYCQVAGATG 258
            :.|            .:::.|..|                     .||..::.:.::.:|...:.
Zfish   432 QEA------------GRELVIPCA---------------------ASGDPEIPTIQWRKVGKPSR 463

  Fly   259 ALHRALLQQHNNIGERLSHINPDWSEEDVFL------EARRIITATIQHITYNEFLPLVLGQETT 317
            :.|..|               |..|.:.|.|      |...:.|..:..||.:..| .|:|....
Zfish   464 SKHNLL---------------PSGSLQFVSLSKEDHGEWECVATNVVTSITASTRL-FVIGTSPH 512

  Fly   318 AKEGLRLTAEKHSSNYS--SSVRGGIYNEFATAAMPAFWSMYPPEMLAKKMSAHELLSIAALQKS 380
            |...:.::|...|:|.|  ....||....|:.      |  |.|..:...:..|:.|||.
Zfish   513 APTNVHVSASTSSANVSWEPGYDGGFEQTFSV------W--YGPVKVKNDVGTHDWLSIP----- 564

  Fly   381 LVPSQTNAEGWSELALAVHRGRDHGVASYVHALDLCERRFADQSAANVSFDTLAQ--VSNIP-EE 442
             ||.       |::.|.|     .|:          |.:.|.|      |..|||  :...| .|
Zfish   565 -VPG-------SQMWLVV-----QGL----------EPKTAYQ------FSVLAQNKLGTGPFSE 600

  Fly   443 YITNLRDIYQNANDIDLLVGALLEEPVVGALFGPTISCLLSLQFEQ------------LKQTDRF 495
            .:|.....|..:.          .||:|  |..|. .||.:.:.:|            ....||:
Zfish   601 VVTVTTGGYPIST----------PEPLV--LLTPP-RCLTANRTQQGVLLTWLPPANHTSPIDRY 652

  Fly   496 WYENEIPPSSFTLDQLKSIRQTTL--SGLLCGSHQVSTAQSKAFILEDNYLN------SILDCDQ 552
            ..|..:......||.|....:|.:  ..|:    |.|..:.:|..:.|:.::      .:...|.
Zfish   653 VIEFRLGEKWEVLDDLIPATETEIIARDLI----QDSWYEFRALAIMDDLVSESSNVVGVSSTDP 713

  Fly   553 LPKFDLKPWQVNPEDEVHVEHVEVEPATKEAIAELSPELIEAAV-----------ERAKQELEER 606
            .|     |.:::.|.       ..:|.....:|.:.  .:.||:           ::.:::|:.:
Zfish   714 FP-----PTEISDEG-------LAKPVVAGIVATIC--FLAAAILFSTLAACFVNKQHRRKLKRK 764

  Fly   607 KRFEYEVWRTKGGI---------------------SARSPDGTAASFSKANLAALNLANS---SL 647
            :.....:..|:..|                     |:..|..|:...|...::..::|:|   ||
Zfish   765 RDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSL 829

  Fly   648 -----------------------IFELTSNEIVKTLNHITRRKRQIFNP---------NQNAFNR 680
                                   :::.|...|......:::.:.::..|         .:...:.
Zfish   830 ASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDP 894

  Fly   681 NELTDTLQTVDISGLLGGAQKQLDTCPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLL 745
            |::..:|:...|.|.  ...::.|..||..|..:.|.....|......||......|.:..|.:.
Zfish   895 NDIDSSLKPRRIEGF--PFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQ 957

  Fly   746 PAQYEDGISAPRLTGVTGTALPNPRTISTTIHPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKG 810
            |..|......|    :.|.::.....:..|....:|:.|..:.  ...|..::.....: .:|..
Zfish   958 PPAYSPRFQRP----MEGMSISEGSRLQATGQSRVSHFHRVFP--PGPFYGYIGSGAEV-ELHPP 1015

  Fly   811 FHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYP-------EVNV----TSGERFCFPSMRSLPG 864
            |:  :|...|.:|..:..|.   :| |.|.|.:|       |:.:    .||.  ..|.:.|.|.
Zfish  1016 FY--MPDVSPRSSAMSSSPS---YP-PEGPFRHPTIPEEREELRIHQYGASGH--ALPLVHSPPS 1072

  Fly   865 QQSL--------------GPR 871
            .:|.              |||
Zfish  1073 SRSTEIWQPPDFPFLGQEGPR 1093

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139	85/419 (20%)
		An_peroxidase_like	209..524	CDD:265428	66/339 (19%)
		An_peroxidase	719..1245	CDD:281139	34/178 (19%)
		peroxinectin_like	871..1245	CDD:188655	1/1 (100%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652
		I-set	139..225	CDD:254352
		I-set	229..321	CDD:333254
		Ig	345..415	CDD:325142	10/41 (24%)
		Ig	438..503	CDD:319273	15/100 (15%)
		FN3	511..606	CDD:238020	31/136 (23%)
		FN3	622..706	CDD:238020	16/88 (18%)
		Atrophin-1	<924..1361	CDD:331285	35/185 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900