Protein Alignment CG10211 and ptgs2b

DIOPT Version :10

• Sequence 1: NP_609883.1
• Gene: CG10211 / 35106
• FlyBaseID: FBgn0032685
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: NP_001020675.1
• Gene: ptgs2b / 559020
• ZFINID: ZDB-GENE-041014-323
• Length: 606
• Species: Danio rerio
• Alignment Length: 646
• Identity: 137/646 - (21%)
• Similarity: 235/646 - (36%)
• Gaps: 149/646 - (23%)

  Fly   706 CPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPR-LTGVTGTALPNP 769
            |..|.|.....:...:.:..|:..|...:|::.||               |. ||.|..:..|:|
Zfish    24 CSHPCQNRGVCTEMGSDAYECDCTRTGYYGQNCTT---------------PEFLTWVKVSLKPSP 73

  Fly   770 RTIS--TTIHPDISNLHTRYSLM---VMQF-----AQFVDHDLTLTPIHKGFHESIPSCRPCNSR 824
            .|:.  .|....:.|:....|.:   :|::     |..:|...|....: |:.............
Zfish    74 NTVHYILTHFKSLWNIINNVSFLRNGIMRYVLTSRAHLIDSPPTFNADY-GYKSWEAYSNLSYYT 137

  Fly   825 QTVHPECNPFPVP---AGDFYYPEVNVTS-----------------------GERFCFPSMRSLP 863
            :|:.|.....|.|   ||....|:|.:.:                       .:.|.....:|
Zfish   138 RTLPPVPRDCPTPMGVAGKKELPDVKMLAEKLLLRRKFIPDPQRTNLMFAFFAQHFTHQFFKS-- 200

  Fly   864 GQQSLGPRDQINQNTHFLDGSMVYGETTCLSNKLRGFSGRMNSTQVRGKELLP-----------L 917
             ....||......| |.:|.:.:||:.....:|||.|.......|:...|:.|           .
Zfish   201 -DMKKGPAFTTALN-HGVDLAHIYGQNLDRQHKLRLFKDGKLRYQILDGEVYPPTVSEVQVDMHY 263

  Fly   918 GPH-PECKSRNGLCFLGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKI 981
            .|| ||.:.     |..|.:.....|||....|.:||||||:.:.|:..:|.|:.|:||..:|.|
Zfish   264 PPHVPESRR-----FAVGHEAFGLVPGLMMYATIWLREHNRVCDILKQEHPDWDDERLFQTSRLI 323

  Fly   982 VSAQVQHIVFNEFLPRILSWNAVNLYGLKLLPQGYY--KDYNPSCSPIVFNEFAAAAFRIG---H 1041
            :..:...||..:::..:               .|||  ..::|.   ::|||......||.   :
Zfish   324 LIGETIKIVIEDYVQHL---------------SGYYFKLKFDPE---LLFNERFQYQNRISSEFN 370

  Fly  1042 SLLRPHIPRLSVQHQPVEPPLLLRDGFFRMDA-------LLQPGII-DEILRGLVATPMETLDQF 1098
            :|...|         |:.|     |.|...|.       |....|: |..:..||    |:.::.
Zfish   371 TLYHWH---------PLMP-----DDFHIQDEVYNYQQFLFNTSILTDYGVNSLV----ESFNKQ 417

  Fly  1099 ITGEVTNHLFEDRKIPFSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREIPTEVI 1163
            |.|.|..    .|.:..:.:.:...:|:.:|.....|.|.||...|:|...::.:::.|  .|:.
Zfish   418 IAGRVAG----GRNVAPAVLRVAIKSIENSRQMRYQSINAYRKRFNMKPYRSFEEMTGE--KEMA 476

  Fly  1164 NRFQKIYASVDDIDLFPGAMTERPLQGGLVGPTLA------CIIGIQFRQLRKCD-RFWYENQNP 1221
            ...:::|..||.::|:.|.:.|:|....:.|.|:.      .:.|:....:  |. .:|    .|
Zfish   477 AELEEMYGDVDAVELYAGLLVEKPRSNAIFGETMVEMGAPYSLKGLMGNPI--CSPEYW----KP 535

  Fly  1222 EVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDLPSNFLNPRVPC---ASMPQIDLN 1279
            .....:.....|...:|..:||.|  :.|....|:|.:|:  :...:|.   ||..|.|.|
Zfish   536 STFGGKVGFEIVNSASLQNLVCNN--VNGPCPMASFYVPN--VKDSLPTTINASTSQSDRN 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_609883.1	An_peroxidase	69..537	CDD:460804
		An_peroxidase	719..1257	CDD:460804	126/606 (21%)
ptgs2b	NP_001020675.1	EGF_CA	21..57	CDD:238011	6/32 (19%)
		prostaglandin_endoperoxide_synthase	77..565	CDD:188648	113/547 (21%)