DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10211 and Irc

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_001262653.1	Gene:	Irc / 42049	FlyBaseID:	FBgn0038465	Length:	697	Species:	Drosophila melanogaster

Alignment Length:	728	Identity:	208/728 - (28%)
Similarity:	302/728 - (41%)	Gaps:	157/728 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   643 ANSSLIFELTSNEI--------VKT-LNHITRRKRQIFNPNQNAFNRNELTDTLQTVDI---SGL 695
            ||||.......|.|        |:| |:.:.|:||              |.|.|...||   :|.
  Fly    24 ANSSRDVNAELNRIPASKWLQYVETALDSVNRQKR--------------LEDNLLGSDITVKNGS 74

  Fly   696 LGGAQKQLDTCPEPSQQCD-------ANSPFRTLSGRC--NNLRNPNW-----------GKSLTT 740
            |..|| .|||.|..:.:.|       ..|.....:..|  ||:.....           |.||.|
  Fly    75 LSHAQ-LLDTLPSLASKKDNKLALKILKSSLLVFNSECLPNNIDGDKCRSYLEQKPLPEGSSLRT 138

  Fly   741 ---------------FSRLL-PAQYEDGI------SAPRLTGVTGTALPNPRTISTTIH-PD--- 779
                           |.||| .:.|.:|.      |..|.|      :|...:||..:: ||
  Fly   139 ECENSLKGNREGHYAFRRLLGSSHYRNGFYQMFPNSGRRET------VPAAWSISKELYEPDHIQ 197

  Fly   780 ISNLHT---RYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCRPCNSRQTV-------HPECNPF 834
            ||...|   ..:|.:.|:||||:|||: .|:.:......|.  .|.||..:       ||.|.|.
  Fly   198 ISKQQTFESNSNLALPQWAQFVEHDLS-KPVSQSMSNGAPI--ECCSRDQINLQPRHHHPACAPI 259

  Fly   835 PV-PAGDFYYPEVNVTSGERFCFPSMRS--LPGQQSLGPRDQINQNTHFLDGSMVYGETTCLSNK 896
            .. |.|.:..|.         |...:||  .....:.|..:|:||.|..||.|.:||.|.....|
  Fly   260 LYQPGGKYDVPS---------CLNYVRSALAVADCNFGGAEQLNQATGSLDLSQLYGFTAAAERK 315

  Fly   897 LRGFSGRMNSTQVRGK---ELLPLGPHPECKS-------RNGLCFLGGDDRASEQPGLTAIHTAF 951
            ||...|.:..:..||:   .|||:....|..|       .:|.||..||.|.:..|....|:|.|
  Fly   316 LRVLEGGLLRSTPRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTIF 380

  Fly   952 LREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVNLYGLKLLPQGY 1016
            :|.||::...|:..||.|:.|:||..|:.:.....:.:|..|:||.:|        |.|:..:..
  Fly   381 MRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVL--------GQKMSSEIR 437

  Fly  1017 YKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSV-----------QHQPVEPPLLLRDGFFR 1070
            .|..|.:..  |.||||.||.|...|:|...:..|:.           |:..:...|..::.|..
  Fly   438 RKQPNRALE--VSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFEL 500

  Fly  1071 MDALLQPGI------IDEILRGLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRAR 1129
            .:.:.:|.:      ::.||..|:......:|...:|.|..|  :|.|...:  |::|.:|||.|
  Fly   501 KEEIYKPKLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWH--KDTKPTHA--DILAFDIQRGR 561

  Fly  1130 DHGIPSYNNYRALCNLKR-ATNWNDLSREIPTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLV 1193
            |||:..|..|...|.|.| ..:|.|....||::|:::.:.||||..|:||..|.::|.|:.|. :
  Fly   562 DHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDLIVGGISENPVHGS-I 625

  Fly  1194 GPTLACIIGIQFRQLRKCDRFWYENQNPEV-KFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAF 1257
            |||.:|||..||..:.|      :||...| |.||. :.:.|.....|::|.|..::...|. .|
  Fly   626 GPTFSCIISEQFVHVLK------QNQQKAVQKHTEL-VEQYRHFNGTKLLCLNSGLSAVPQN-IF 682

  Fly  1258 DLPSNFLNPRVPC 1270
            .||| ..|..|.|
  Fly   683 QLPS-ARNQMVSC 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	172/606 (28%)
		peroxinectin_like	871..1245	CDD:188655	123/402 (31%)
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	165/560 (29%)
Irc	NP_001262653.1	An_peroxidase_like	290..637	CDD:265428	111/361 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920