DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10211 and mpx

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_001338766.1	Gene:	mpx / 337514	ZFINID:	ZDB-GENE-030131-9460	Length:	893	Species:	Danio rerio

Alignment Length:	688	Identity:	236/688 - (34%)
Similarity:	338/688 - (49%)	Gaps:	108/688 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   656 IVKTLNHITRRKRQIFNPNQNAFNRNELT-DTLQTVDISGLLGGAQKQLDTCPEPSQQCDANSPF 719
            :.:||..|:.:...:...:.||  .|.|| |.|||:.   .:.|.:.|  |.|...:.....:.:
Zfish    87 MAQTLRLISEKAHHVHKRSINA--TNLLTQDELQTIT---RMTGCEAQ--TRPPSCRTTPLINKY 144

  Fly   720 RTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTG------VTGTALPNPRTIS----T 774
            ||.||.|||.:||..|.|.|.|:|.|||||||.:|.|:  |      ..|.|||..|.:|    .
Zfish   145 RTASGVCNNRKNPLLGASNTPFARWLPAQYEDAVSQPK--GWDPNKLYNGAALPMVRLVSNRILA 207

  Fly   775 TIHPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPS------CRPCNSRQTVHPECNP 833
            |...||.:.|. ::.|:..|.|:||||||.||    |..||.|      |.  ||.:...| |.|
Zfish   208 TADADIESDHD-FTFMLTIFGQWVDHDLTFTP----FSPSIRSFSNGIDCE--NSCERSEP-CFP 264

  Fly   834 FPVPAGDFYYPEVNVTSGERF----CFPSMRSLP----GQQSL------GPRDQINQNTHFLDGS 884
            ...|.||           :|.    |.|..||.|    |..:.      ..|:|||..|.:||..
Zfish   265 ISAPPGD-----------QRLRPNTCLPVFRSAPTCGSGHTAYMFGEVPNVREQINTLTAYLDAG 318

  Fly   885 MVYGETTCLSNKLRGFSG-----RMNST-QVRGKELLPLGPHPE--CKSRNGL----------CF 931
            .|||....|:.:||..:.     |:|:. :..|:||||......  |.:|..:          ||
Zfish   319 QVYGSEDGLAKELRDLTNDGGLLRVNNRFKDNGRELLPFTSVNTNLCATRQKILNDSTLTEVPCF 383

  Fly   932 LGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLP 996
            :.||.|.:|.|.|.::||.|:|||||:...|..:||.|:.|.|:..|||||.|..|.:|..|:||
Zfish   384 IAGDARVNENPALNSLHTLFVREHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLP 448

  Fly   997 RILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRL--SVQHQPVE 1059
            .|:..:|.|.:      .|.|..||.:..|.:.|.||.||||..|..::|.|.||  :.::.|..
Zfish   449 LIVGPDAYNRH------LGPYPGYNENVDPTIANVFATAAFRFAHLTIQPFIFRLDENYKNHPQF 507

  Fly  1060 PPLLLRDGFFRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFEDRKIPFS---GID 1119
            |.:.|.:.||....::..|.||.:||||:..|  :.|.|..:...:...||     .|:   .:|
Zfish   508 PSVPLYEAFFSPWRVIFEGGIDPVLRGLIGRPAKLNTQDHMLVNALRERLF-----AFTSHIALD 567

  Fly  1120 LIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREI-PTEVINRFQKIYASVDDIDLFPGAM 1183
            |.:||:||.|||.||.||.:|..|.|....|..:|:..: .||:..:..::|.:.::||::.|.:
Zfish   568 LASLNMQRGRDHAIPGYNAWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDVWLGGV 632

  Fly  1184 TERPLQGGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCEN--- 1245
            .|....||.||...||:|..||:::|..||.|:|:..   .||..|...:..|:||:|:|:|
Zfish   633 AEPFAPGGRVGSLFACLISRQFQKIRDGDRLWFESNG---VFTTKQKTALASVSLARIICDNTGI 694

  Fly  1246 LEITGDMQRAAFDLPSNFLNPRVPCASMPQIDLNAWRE 1283
            |::..|..|  |..|:||:|    |.::|..||..|:|
Zfish   695 LKVPRDPFR--FRSPANFVN----CGNIPAFDLEPWKE 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	205/581 (35%)
		peroxinectin_like	871..1245	CDD:188655	140/399 (35%)
mpx	NP_001338766.1	An_peroxidase_like	160..726	CDD:326323	210/606 (35%)
mpx	NP_001338766.1	C1q	772..890	CDD:306816
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820