DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10211 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	1057	Identity:	198/1057 - (18%)
Similarity:	321/1057 - (30%)	Gaps:	377/1057 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 SLQFEQLKQTDRFWYENEIPPSSFTLDQLKSIRQTTLSGLLCGSHQVSTAQSKAFILEDNYLNSI 547
            ||:.||::..|:.|||.::    ..|||                 |..|..:.:::        .
  Rat    97 SLRLEQVRSEDQGWYECKV----LMLDQ-----------------QYDTFHNGSWV--------H 132

  Fly   548 LDCDQLPKFDLKPWQVNPEDEVHVEHVEVEPATKEAIAELSPELIEAAVERAKQELEERKRFEYE 612
            |..:..|.|...|.|       ::|..|....|....|..:|:.|                   .
  Rat   133 LTINAPPTFTETPPQ-------YIEAKEGGSITMTCTAFGNPKPI-------------------V 171

  Fly   613 VWRTKGGISARS-----PDG--TAASFSKANLAALNLANSSLIFELTSNEIVKTLNHITRRKRQI 670
            .|..:|.:.:.|     .||  |..|.|:.:..|......|:     ..|.|.|.:.:.:....|
  Rat   172 TWLKEGTLLSASGKYQVSDGSLTVTSVSREDRGAYTCRAYSI-----QGEAVHTTHLLVQGPPFI 231

  Fly   671 FNPNQNAFNRNELTDTLQTVDISGLLGGAQKQLDTCPEPSQQ---------CDANSPFRT-LSGR 725
            .:|.:|.           ||:||      |..|.||...:..         .|.|..|:. |..|
  Rat   232 VSPPENI-----------TVNIS------QDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLR 279

  Fly   726 CNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVTGTALPNPRTISTTIHPDISNLHTRYSLM 790
            ...|.:    .:|..| |:.|   ||   |.:.|.|...:|....:.|       :.|..:|...
  Rat   280 VRILID----GTLIIF-RVKP---ED---AGKYTCVPSNSLGRSPSAS-------AYLTVQYPAR 326

  Fly   791 VMQFAQFVDHDLTLTPIHKGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFC 855
            |:.....:     ..|:  |.|..|              .|   ||.|    .|...|....:
  Rat   327 VLNMPPVI-----YVPV--GIHGYI--------------RC---PVDA----EPPATVVKWNK-- 361

  Fly   856 FPSMRSLPGQQSLGPRDQINQNTHFLDGSM--------VYGETTCLSNKLRGFSGRMNSTQVRGK 912
              ..|.|..:::||       .|...|||:        ..|..||:.....|..|:....::..|
  Rat   362 --DGRPLQVEKNLG-------WTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLK 417

  Fly   913 E-----LLPLGPHPECKSRNGL--CFLGGDD------RASEQPGLTAIHTAFLREHNRIVEG--- 961
            :     :||...:.:...|..|  |...||.      |...:|..:        :||.:..|
  Rat   418 DPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRS--------KHNALPSGSLQ 474

  Fly   962 ------------------------------LRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLP 996
                                          :.|.:||..|....|     ||....::
  Rat   475 FRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVH-----VSMTTANV------- 527

  Fly   997 RILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPVEPP 1061
               ||.           .||...|..:.| :.:......|....|..|     .|||   |:.|.
  Rat   528 ---SWE-----------PGYDGGYEQTFS-VWYGPLMKRAQFGPHDWL-----SLSV---PLGPS 569

  Fly  1062 LLLRDGF-----FRMDALLQ----PGIIDEI-----LRGLVATP----METLDQFITGEVT---- 1104
            .||.|..     ::...|.|    .....|:     |...|.||    :.|..:.:|...|
  Rat   570 WLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGV 634

  Fly  1105 --------NHLFE-----------------DRKIPFSGIDLIALNIQRARDHGIPSYNNYRALCN 1144
                    ||.|.                 |..||.:..:..      |:|....::..:|.|..
  Rat   635 LLSWLPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGEFF------AKDLSQDTWYEFRVLAV 693

  Fly  1145 LKRATNWNDLSREIPTEVINRFQKIYASVDDIDLFPGA-MTE----RPLQGGLVGPTLACIIGIQ 1204
            ::      ||..| |:.:        |.|...|:||.. :|:    ||:..|:|.........|.
  Rat   694 MQ------DLISE-PSNI--------AGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAIL 743

  Fly  1205 FRQLRKC------DRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENL-------EITGDMQRAA 1256
            |..|..|      .|.....::|.:..|..:.:....::..|:..|::       |.:.|..:.|
  Rat   744 FSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPA 808

  Fly  1257 FDLPSNFLNPRVPCASMPQIDLNAWRENVQGCQIGNRNVRVGESAFPSPCTSCVCSAEGAQCASL 1321
               ....|:|      ..:.:|:.:::..:.  |.:|...|.::...:..|:.:
  Rat   809 ---AKRMLSP------TREKELSLYKKTKRA--ISSRKYSVAKAEAEAEATTPI----------- 851

  Fly  1322 RITDCGQLIRQWPKEAILRDEVCNSQCGIYLTGQQASGFNPQQRQGQAQPRVTRSRNQN------ 1380
                  :||.:.|....:...   |:....:.|::..|| |...:....|...:|..:|
  Rat   852 ------ELISRGPDGRFVMGP---SEMEPSVKGRRIEGF-PFAEETDMYPEFRQSDEENEDPLVP 906

  Fly  1381 ----LFKFPDLTPFIAS 1393
                ..| |.|||..:|
  Rat   907 TSVAALK-PQLTPMSSS 922

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139	11/40 (28%)
		An_peroxidase_like	209..524	CDD:265428	11/40 (28%)
		An_peroxidase	719..1245	CDD:281139	120/638 (19%)
		peroxinectin_like	871..1245	CDD:188655	88/485 (18%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021	7/26 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044		2/5 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	8/17 (47%)
		I-set	139..225	CDD:369462	23/116 (20%)
		Ig	229..321	CDD:386229	29/126 (23%)
		Ig	<353..414	CDD:386229	14/71 (20%)
		Ig	438..502	CDD:319273	9/71 (13%)
		FN3	510..605	CDD:238020	26/129 (20%)
		FN3	621..703	CDD:238020	16/94 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821		9/67 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900