Protein Alignment CG10211 and Epx

DIOPT Version :10

• Sequence 1: NP_609883.1
• Gene: CG10211 / 35106
• FlyBaseID: FBgn0032685
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: NP_001100507.1
• Gene: Epx / 303414
• RGDID: 1311882
• Length: 715
• Species: Rattus norvegicus
• Alignment Length: 757
• Identity: 260/757 - (34%)
• Similarity: 374/757 - (49%)
• Gaps: 135/757 - (17%)

  Fly   581 KEAIAELSPELIEAAVERAKQELEERKRFEYEVWRTKGGISARSPDGTAASFSKANLAALNLANS 645
            ::.||| :..|::.|..|.::.:         |.|.:.|  :.||....|.| |..:||
  Rat    37 QDCIAE-AKLLVDTAYNRTQKSI---------VQRLQSG--SASPMDLLAYF-KQPVAA------ 82

  Fly   646 SLIFELTSNEIVKTLNH------ITRRKRQIFNPNQN-AFNRNELTDTLQTVDISGLLGGA---- 699
                   :..:|:..::      :...|.|   |.:: .||   :||.|....:. ||..|
  Rat    83 -------TRRVVQAADYMHVALGLLEEKLQ---PQESRPFN---VTDVLTEPQLR-LLSQASGCA 133

  Fly   700 -QKQLDTCPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVT- 762
             |.|::.|         ::.:||::|||||.|.|..|.|....:|.|||:|||..|.|  .|.|
  Rat   134 LQDQVEKC---------SNKYRTITGRCNNRRRPWLGASNQALARWLPAEYEDHRSLP--FGWTP 187

  Fly   763 -----GTALPNPRTISTTIHPDISNLHTRY-----------SLMVMQFAQFVDHDLTLT---PIH 808
                 |..||..|.:|..|        .|:           |||.||:.||:||||..|   |..
  Rat   188 GKRRNGFLLPLVRAVSNQI--------VRFPSKKLTSDQGRSLMFMQWGQFIDHDLDFTPESPAR 244

  Fly   809 KGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPG--QQSLGPR 871
            ..|:..:...:.|...    |.|.|..:|..|   |.:   ..:|.|.|..||.|.  |.....|
  Rat   245 VTFNMGVDCEKTCAQL----PPCFPIKIPPND---PRI---KSQRDCIPFFRSAPACPQNRNKVR 299

  Fly   872 DQINQNTHFLDGSMVYGETTCLSNKLR------GFSGRMNSTQVRGKELLPLGPHPE--CKSRNG 928
            :|||..|.|:|.|||||....|:.:||      |........|..|:.|||.....|  |...|.
  Rat   300 NQINSLTSFVDASMVYGSEVSLALRLRNRTNYLGLLATNQQFQDNGRALLPFDNLHEDPCLLTNR 364

  Fly   929 L----CFLGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHI 989
            |    |||.||.||||.|.|.|:||.|:|||||:...|:.:||||:|::|::.|||||.|.||.|
  Rat   365 LVRIPCFLAGDSRASETPKLAALHTLFVREHNRLATELKRLNPHWSGDKLYNEARKIVGAMVQII 429

  Fly   990 VFNEFLPRILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQ 1054
            .:.:|||.:|....:.    :.|  |.|:.|..:..|.|.|.| ..|||.||::|:|.:.||..|
  Rat   430 TYRDFLPLVLGKARMR----RTL--GPYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487

  Fly  1055 HQPVEP--PLLLRDGFFRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFED-RKIP 1114
            ::...|  .:||...||....::..|.||.|||||:|||  :...|..:..|:.:.||:. |:|
  Rat   488 YRTSAPNSHVLLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRRI- 551

  Fly  1115 FSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREIPT-EVINRFQKIYASVDDIDL 1178
              |:||.|||:||:||||:|.||.:|..|.|.:..|...|||.:.. .:..:|..:|.:.|:||:
  Rat   552 --GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNRNLARKFLNLYKTPDNIDI 614

  Fly  1179 FPGAMTERPLQGGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVC 1243
            :.||:.|..|.|..|||.|||:...|||:.|..||||::...   .||:.|...:|:::|::|||
  Rat   615 WVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWG---VFTKRQRKALRRISLSRIVC 676

  Fly  1244 ENL---EITGDMQRAAFDLPSNFLNPRVPCASMPQIDLNAWR 1282
            :|.   .::.|:.||.. .|..|    |.|:.:|:::|:|||
  Rat   677 DNTGISTVSRDIFRANI-YPQGF----VSCSRIPKLNLSAWR 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_609883.1	An_peroxidase	69..537	CDD:460804
		An_peroxidase	719..1257	CDD:460804	220/580 (38%)
Epx	NP_001100507.1	myeloperoxidase_like	287..699	CDD:188656	168/429 (39%)