Protein Alignment CG10211 and Mpo

DIOPT Version :10

• Sequence 1: NP_609883.1
• Gene: CG10211 / 35106
• FlyBaseID: FBgn0032685
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: NP_001388741.1
• Gene: Mpo / 303413
• RGDID: 1592081
• Length: 718
• Species: Rattus norvegicus
• Alignment Length: 814
• Identity: 263/814 - (32%)
• Similarity: 393/814 - (48%)
• Gaps: 152/814 - (18%)

  Fly   519 LSGLLCGSHQVSTAQSKAFILEDNYLNS-ILDCDQLPKFDLKPWQVNPEDEVHVEHVEVEPATKE 582
            |:|||.....:.|:......|.....|| :|||
  Rat     7 LAGLLAPLAMLQTSTGATPALPGEVANSVVLDC-------------------------------- 39

  Fly   583 AIAELSPELIEAAVERAKQELEERKRFEYEVWRTKGGISARSPDGTAA-----SFSKANLAALNL 642
              .|.:..|:..|.:..::.:::               |.||  |:|:     |:.|..:|....
  Rat    40 --MEEAKRLVNKAYKERRESIKQ---------------SLRS--GSASPMELLSYFKQPVAGTRT 85

  Fly   643 ANSSLIFELTSNEIVKTLNHITRRKRQIFNPNQNAFNRNELTDTLQTVDISGL---LGGAQKQLD 704
            |       :.:.:.:.....:.:||.|...|  ..||   :||.|....::.|   .|.|.:.:.
  Rat    86 A-------VRAADYLHVALDLLKRKLQPLWP--RPFN---VTDVLTPAQLNLLSVSSGCAYQDVG 138

  Fly   705 -TCPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVT------ 762
             |||...:       :||::|.|||.|:|..|.|...|.|.|||:||||||.|  .|.|
  Rat   139 VTCPPQDK-------YRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGISLP--FGWTPKVNRS 194

  Fly   763 GTALPNPRTISTTI----HPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCR---- 819
            |..:|..|.:|..|    :..::....| :||.||:.||:|||:||||        .|:.|
  Rat   195 GFKVPLARQVSNAIVRFPNDQLTKDQER-ALMFMQWGQFLDHDITLTP--------EPATRFSFL 250

  Fly   820 ---PCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPG--QQSLGPRDQINQNTH 879
               .|.:.......|.|..:|..|   |.:   ..::.|.|..||.|.  ..::..|:|||..|.
  Rat   251 TGLNCETSCLQQQPCFPLKIPPND---PRI---KNQKDCIPFFRSCPACTGSNITIRNQINALTS 309

  Fly   880 FLDGSMVYGETTCLSNKLRGFSGRMNSTQV------RGKELLPLGP-HPE-C----KSRNGLCFL 932
            |:|.|.|||....|:.:||..:.::....|      .|:.|||... |.: |    :|....|||
  Rat   310 FVDASGVYGSEDPLARRLRNLTNQLGLLAVNTRFQDNGRALLPFDSLHDDPCLLTNRSARIPCFL 374

  Fly   933 GGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPR 997
            .||.|:||.|.||::||.|:|||||:...|:.:||.||||:|:..|||||.|.||.|.:.::||.
  Rat   375 AGDMRSSEMPELTSMHTLFVREHNRLATELKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPL 439

  Fly   998 ILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPV--EP 1060
            :|...|:..|    |||  |:.||.|..|.:.|.| ..|||.||:|::|.:.||..|::..  .|
  Rat   440 VLGPAAMKKY----LPQ--YRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNQYRSTGPNP 497

  Fly  1061 PLLLRDGFFRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFEDRKIPFSGIDLIAL 1123
            .:.|...||....::..|.||.|||||:|||  :...:|....|:...|||  ::...|:||.||
  Rat   498 RVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFE--QVMRIGLDLPAL 560

  Fly  1124 NIQRARDHGIPSYNNYRALCNLKRATNWNDLSREIPT-EVINRFQKIYASVDDIDLFPGAMTERP 1187
            |:||:||||:|.||.:|..|.|.:.:...:|...:.. |:..:....|.:.::||::.|.::| |
  Rat   561 NMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSE-P 624

  Fly  1188 LQ-GGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGD 1251
            |: .|.||..|||:||.|||:||..||||:|  ||.| |::.|...:..::|.:|:|:|..||..
  Rat   625 LEPNGRVGQLLACLIGTQFRKLRDGDRFWWE--NPGV-FSKQQRQALATISLPRIICDNTGITTV 686

  Fly  1252 MQRAAFDLPSNFLNPR--VPCASMPQIDLNAWRE 1283
            .:...|...|   :||  |.|.::|:::|.:|:|
  Rat   687 SKNNIFMSNS---HPRDFVSCNTLPKLNLASWKE 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_609883.1	An_peroxidase	69..537	CDD:460804	5/17 (29%)
		An_peroxidase	719..1257	CDD:460804	215/574 (37%)
Mpo	NP_001388741.1	myeloperoxidase_like	289..702	CDD:188656	165/428 (39%)