DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10211 and Ptgs2

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_058928.3	Gene:	Ptgs2 / 29527	RGDID:	620349	Length:	604	Species:	Rattus norvegicus

Alignment Length:	581	Identity:	122/581 - (20%)
Similarity:	211/581 - (36%)	Gaps:	160/581 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   716 NSPF-------RTLSGRCNNLRNP----------NWG--KSLTTFSRLLPAQYEDGISAPRLTGV 761
            |.||       ..|:.|.:.:.:|          :|.  .:|:.::|.||...:|   .|...||
  Rat    90 NIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADD---CPTPMGV 151

  Fly   762 TGT-ALPNPRTISTTI------HPDISNLHTRYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCR 819
            .|. .||:.:.:...:      .||....    ::|...|||...|....|...:|
  Rat   152 KGNKELPDSKEVLEKVLLRREFIPDPQGT----NMMFAFFAQHFTHQFFKTDQKRG--------- 203

  Fly   820 PCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPG-QQSLGPRDQINQNTHFLDG 883
                                                       || .:.||         |.:|.
  Rat   204 -------------------------------------------PGFTRGLG---------HGVDL 216

  Fly   884 SMVYGETTCLSNKLRGFSGRMNSTQVRGKELLP-----------LGPH-PECKSRNGLCFLGGDD 936
            :.|||||....:|||.|.......||.|.|:.|           ..|| ||     .|.|..|.:
  Rat   217 NHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPE-----HLRFAVGQE 276

  Fly   937 RASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSW 1001
            .....|||....|.:||||||:.:.|:..:|.|:.|:||..:|.|:..:...||..:::..:..:
  Rat   277 VFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGY 341

  Fly  1002 NAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIG---HSLLRPHIPRLSVQHQPVEPPLL 1063
            :    :.||..|:            ::||:......||.   ::|...| |.|.......:....
  Rat   342 H----FKLKFDPE------------LLFNQQFQYQNRIASEFNTLYHWH-PLLPDTFNIEDQEYT 389

  Fly  1064 LRDGFFRMDALLQPGIIDEILRGLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRA 1128
            .:...:....||:.|:         |..:|:..:.|.|.|..    .|.:|.:...:...:|.::
  Rat   390 FKQFLYNNSILLEHGL---------AHFVESFTRQIAGRVAG----GRNVPIAVQAVAKASIDQS 441

  Fly  1129 RDHGIPSYNNYRALCNLKRATNWNDLSREIPTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLV 1193
            |:....|.|.||...:||..|::.:|:.|  .|:....:.:|..:|.::|:|..:.|:|....:.
  Rat   442 REMKYQSLNEYRKRFSLKPYTSFEELTGE--KEMAAELKALYHDIDAMELYPALLVEKPRPDAIF 504

  Fly  1194 GPTLA------CIIGIQFRQLRKCD-RFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLE 1247
            |.|:.      .:.|:....:  |. ::|    .|.....|.....:...::..::|.|::
  Rat   505 GETMVELGAPFSLKGLMGNPI--CSPQYW----KPSTFGGEVGFRIINTASIQSLICNNVK 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	119/574 (21%)
		peroxinectin_like	871..1245	CDD:188655	90/395 (23%)
Ptgs2	NP_058928.3	EGF	21..53	CDD:278437
Ptgs2	NP_058928.3	prostaglandin_endoperoxide_synthase	75..562	CDD:188648	122/581 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810