DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10211 and hpx-2

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_506432.1	Gene:	hpx-2 / 179880	WormBaseID:	WBGene00008627	Length:	718	Species:	Caenorhabditis elegans

Alignment Length:	804	Identity:	250/804 - (31%)
Similarity:	367/804 - (45%)	Gaps:	142/804 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 TLSGLLCGSHQVSTAQSKAFILEDNYLNSILDCDQLPKFDLKPWQVNPEDEVHVEHVEV------ 576
            |:..|.|.:.:|:....:  |:||..:.::         |.:..: |.|.|...:|:.|
Worm    11 TILFLKCATFEVNEETER--IVEDAVMRAL---------DSRASE-NSESEQTSQHIIVSQQANS 63

  Fly   577 ------------EPATKEAIAELSPELIEAA---VERAKQELEERKRFEYEVWRTKGGISARSPD 626
                        |.||:..:.|...|::.||   :||.:.|.||.
Worm    64 DSKSAQFTGEVLEEATRILVREFGLEILPAANEVIERWRNEEEEL-------------------- 108

  Fly   627 GTAASFSKANLAALNLANSSLIFELTSNEIVKTLNH--ITRRKRQ-IFNPNQNAFNRNELTDTLQ 688
                                    |.|:|...|..|  .||.||. ||...:.|..|
Worm   109 ------------------------LQSSETTTTTEHPDPTRSKRSAIFRSKRQANRR-------- 141

  Fly   689 TVDISGLLGGAQKQLDTCPEPSQQCD--ANSPFRTLSGRCNNLRNPNWGKSLTTFSRLL-PAQYE 750
                             |..|...|:  .::..|:::|.|||.:|.:.|.|::...|:| .|.|.
Worm   142 -----------------CSSPPINCNNRFHTSIRSITGLCNNRQNSDLGNSVSPLRRILGAASYA 189

  Fly   751 DGISAPRLTGVTGTALPNPRTISTTIH---------PDISNLHTRYSLMVMQFAQFVDHDLTLTP 806
            ||:...|...|.|..||:.|.||..||         |.|::||       |...||:.||:...|
Worm   190 DGLGRIRTRSVNGGELPSARLISNRIHDDRNNQVFSPSINHLH-------MIIGQFIAHDVVFMP 247

  Fly   807 IHKGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPGQQSLGPR 871
            ...........|..|||.|.|.|.|.|..:|..|.|:   |..     |....|:|.||::.|.|
Worm   248 SSVARDGGALDCSACNSPQRVSPNCAPITIPRNDPYF---NTP-----CMRLTRALNGQENFGVR 304

  Fly   872 DQINQNTHFLDGSMVYGETTCLSNKLRGF-SGRMNSTQVRGKELLPLGPH-PECKSRNGL-CFLG 933
            .||.||:||||.|.|||...|.:..:|.| .|:|.:....|..|.|...: ..|:|.... ||..
Worm   305 SQIGQNSHFLDLSPVYGSADCEAETVRSFQEGKMLTFDDLGYTLPPQNANDSNCQSSAPFHCFTC 369

  Fly   934 GDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRI 998
            ||.|.|..|.|..:||..::||||:.|.:|...|.:|.||:|...|||:....||||:||::|:.
Worm   370 GDFRNSLHPALIPVHTILIKEHNRLAEQVRVARPRFNDEQIFQLVRKIMIGMWQHIVYNEYIPKY 434

  Fly   999 LSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPVEPPLL 1063
            |....:..:.|:.|..|.::.|:.|..|.:..|||.||||.|||..|...|||:...:|.....|
Worm   435 LPRRTIRNFALRPLRNGVHRGYSTSVDPSISAEFAGAAFRFGHSQSRFDFPRLTENGRPAGNYDL 499

  Fly  1064 LRDGFFRMDA-LLQPGIIDEILRGLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQR 1127
            ..|.|:.... |.:.|..:.::.|:|..|....|::.:..:.|.:||.|....||:||:::||||
Worm   500 GNDIFYADQMYLTRIGGWEPVMNGMVRMPAMKSDRYFSFGIRNQMFEIRGRNGSGVDLVSINIQR 564

  Fly  1128 ARDHGIPSYNNYRALCNLKRATNWNDLSREIPTEVINRFQKIYASVDDIDLFPGAMTERPLQGGL 1192
            .||.|:..|..||.|..|...|::|:|:.....|.|...:.:|:...||||:.|.|.|.||.||.
Worm   565 GRDMGLFPYIQYRQLVGLPTVTSFNELNTTFSQENIQALRNVYSDPADIDLYVGIMLEEPLSGGQ 629

  Fly  1193 VGPTLACIIGIQFRQLRKCDRFWYEN-QNPEVKFTEAQLAEVR-KVTLAKIVCENLEITGDMQRA 1255
            :|||.:.:||.|||.|::.|||:||: ......||:.:::|:| |.:||||:|.|::....:...
Worm   630 LGPTASFMIGEQFRALKRGDRFFYESIAEGTDNFTQEEISELRNKTSLAKIICTNMDFAARINTD 694

  Fly  1256 AFDLPSNFLNPRVPCASMPQIDLN 1279
            .||..|.    :|.|.|:||:|::
Worm   695 IFDHRSR----QVACTSLPQLDID 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139	2/5 (40%)
		An_peroxidase_like	209..524	CDD:265428	2/5 (40%)
		An_peroxidase	719..1245	CDD:281139	199/541 (37%)
		peroxinectin_like	871..1245	CDD:188655	146/379 (39%)
hpx-2	NP_506432.1	An_peroxidase	158..696	CDD:376988	200/552 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920