DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10211 and skpo-3

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	NP_495511.1	Gene:	skpo-3 / 174191	WormBaseID:	WBGene00017968	Length:	1000	Species:	Caenorhabditis elegans

Alignment Length:	663	Identity:	232/663 - (34%)
Similarity:	343/663 - (51%)	Gaps:	80/663 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   662 HITRR------KRQIFNPNQNAFNRNELTDTL---------------------QTVDISGLLGGA 699
            |.||.      .|...|...||..|:.:.|.:                     ||||:..::...
Worm   376 HFTREFTPPPTTRSFINTGSNARCRDIINDPIVAAEDMWRERLVVATEDNTRRQTVDLDQVIRSN 440

  Fly   700 QKQLDTCPEPSQQCDA----NSPFRTLSGRCNNLR-NPNWGKSLTTFSRLLPAQYEDGISAPRLT 759
            .....|.......|:|    |:.||||.|.|||:: .|..|.|...::||||..|::.:|.| :.
Worm   441 TANACTPRLDEADCEANICYNAMFRTLDGTCNNMKGEPLRGASYRPYTRLLPTIYDNEVSEP-VG 504

  Fly   760 GVTGTALPNPRTISTTIHPDISNLHT-RYSLMVMQFAQFVDHDLTLTPIHKGFHESIPSCRPCNS 823
            .:...|.|:||.|:..:....:::.: .|:.::|||.||:.||:..|.:       :||.: ||.
Worm   505 SLFTDARPSPREITRRLTSSQASVESPDYNALIMQFGQFISHDMAKTTL-------VPSSK-CNV 561

  Fly   824 RQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLP--GQQSLGPRDQINQNTHFLDGSMV 886
            .|.:...|...|:.     :.:.|....:..|....||.|  |..:|.||.|:|:||.::|.|.:
Worm   562 CQNITSRCMSVPIT-----FDDSNANFRQAQCIRVSRSSPICGSGNLKPRQQLNENTGYIDASPI 621

  Fly   887 YGETTCLSNKLR-GFSGRMNSTQVRGKELLPLGPHPECKSRNGLC---FLGGDDRASEQPGLTAI 947
            ||.:...|.|.| |.||.:......||..||...: :|::| |.|   |..||.|.:...||:|.
Worm   622 YGSSVHDSKKFRDGNSGFLKLPMFNGKAFLPFDQN-KCRNR-GQCSVIFTAGDSRVNLFVGLSAW 684

  Fly   948 HTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVNLYGLKLL 1012
            ||.|..||||:|...:.:||||:||:|:..|||::.||||.||:.|:||::|..:...:.
Worm   685 HTIFTEEHNRLVTAFKRLNPHWDGERLYQEARKMIGAQVQAIVYREWLPKVLGASFATVV----- 744

  Fly  1013 PQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPVE-PPLLLRDGFFRMDALLQ 1076
              |.|:.|:......|.|||.:||||.||.:::....||....:.:. ..|..:.|....|.|:.
Worm   745 --GDYRGYDSDVDSTVANEFTSAAFRFGHGMIQEFYQRLDNSFRNISFGALPFQKGTLHSDVLVN 807

  Fly  1077 PGIIDEILRGLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRARDHGIPSYNNYRA 1141
            .|.:|.::||:.:..::. .|.:|..||.::       |...||..:||||.||||.|:|..||.
Worm   808 EGGVDPLIRGMFSQNVKR-PQRVTTTVTENM-------FGSTDLSTINIQRGRDHGHPAYVKYRE 864

  Fly  1142 LCNLKRATNWNDLSREI-PTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLVGPTLACIIGIQF 1205
            ||.:..|.|:..||||| .|...|:.|:||.|||.|||:.||:.|.|:..||||||:|||||.||
Worm   865 LCGMGTAFNFEHLSREILNTGTRNKLQEIYGSVDKIDLWVGALLEDPIIRGLVGPTVACIIGPQF 929

  Fly  1206 RQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDLPSNFLNPRVPC 1270
            ::.|..|||:||  ||.| |:..||.|:||.:|::|:|:|......:.|.||.     :...|||
Worm   930 KRTRDGDRFYYE--NPGV-FSRRQLVEIRKSSLSRIICDNTNTISTIPREAFR-----VGHMVPC 986

  Fly  1271 ASMPQIDLNAWRE 1283
            :.:|.:|||.||:
Worm   987 SQIPSMDLNQWRD 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	202/535 (38%)
		peroxinectin_like	871..1245	CDD:188655	155/379 (41%)
skpo-3	NP_495511.1	ShKT	41..75	CDD:214586
skpo-3	NP_495511.1	An_peroxidase	464..978	CDD:376988	204/547 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920