Protein Alignment CG10211 and Epx

DIOPT Version :10

• Sequence 1: NP_609883.1
• Gene: CG10211 / 35106
• FlyBaseID: FBgn0032685
• Length: 1394
• Species: Drosophila melanogaster
• Sequence 2: NP_031972.2
• Gene: Epx / 13861
• MGIID: 107569
• Length: 716
• Species: Mus musculus
• Alignment Length: 757
• Identity: 256/757 - (33%)
• Similarity: 378/757 - (49%)
• Gaps: 120/757 - (15%)

  Fly   582 EAIAELSPELIEAAVER---AKQELEERKRFEYEVWRTKGGISARSPDGTAA-----SFSKANLA 638
            |..|..||..:|.:|.|   |:.:|.....:.:    |:..|..|...|:|:     ::.|..:|
Mouse    22 EGTAPASPSPVEISVLRDCIAEAKLLVDTAYNH----TQKSIMQRLRSGSASPMDLLAYFKQPVA 82

  Fly   639 ALNLANSSLIFELTSNEIVKTLNH----ITRRKRQIFNPNQNAFNRNELTDTLQTVDISGLLGGA 699
            |             :..:|:..::    :...:.::.......||..::....|...:|...|.|
Mouse    83 A-------------TRRVVQAADYMHVALGLLEERLQPRGSRPFNATDVLTEPQLRLLSQASGCA 134

  Fly   700 -QKQLDTCPEPSQQCDANSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVT- 762
             |.|.:.|         ::.:||::|||||.::|..|.|....:|.|||:|||..|.|  .|.|
Mouse   135 LQDQAERC---------SNKYRTITGRCNNKKHPWLGASNQALARWLPAEYEDHRSLP--FGWTP 188

  Fly   763 -----GTALPNPRTISTTIHPDISNLHTRY-----------SLMVMQFAQFVDHDLTL---TPIH 808
                 |..||..|        |:||...|:           :||.||:.||:||||..   :|..
Mouse   189 GKRRNGFLLPLVR--------DVSNQIVRFPSKKLTSDRGRALMFMQWGQFIDHDLDFSPESPAR 245

  Fly   809 KGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYPEVNVTSGERFCFPSMRSLPG--QQSLGPR 871
            ..|...:...:.|...    |.|.|..:|..|   |.:   ..:|.|.|..||.|.  |.....|
Mouse   246 VAFSMGVDCEKTCAQL----PPCFPIKIPRND---PRI---KNQRDCIPFFRSAPACPQNRNKVR 300

  Fly   872 DQINQNTHFLDGSMVYGETTCLSNKLR---GFSGRMNST---QVRGKELLPLGPHPE--C----K 924
            :|||..|.|:|.|||||....|:.:||   .|.|.:.:.   |..|:.|||.....|  |    :
Mouse   301 NQINALTSFVDASMVYGSEVTLALRLRNRTNFLGLLATNQRFQDNGRALLPFDNLHEDPCLLTNR 365

  Fly   925 SRNGLCFLGGDDRASEQPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHI 989
            |....|||.||.|:||.|.|||:||.|:|||||:...||.:||||:|::|::.|||||.|.||.|
Mouse   366 SARIPCFLAGDTRSSETPKLTALHTLFVREHNRLAAELRRLNPHWSGDKLYNEARKIVGAMVQII 430

  Fly   990 VFNEFLPRILSWNAVNLYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQ 1054
            .:.:|||.:|....:.    :.|  |.|:.|..:..|.|.|.| ..|||.||::|:|.:.||..|
Mouse   431 TYRDFLPLVLGRARIR----RTL--GPYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 488

  Fly  1055 HQPVEP--PLLLRDGFFRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFED-RKIP 1114
            ::...|  .:.|...||....::..|.||.|||||:|||  :...|..:..|:.:.||:. |:|
Mouse   489 YRASAPNSHVPLSSVFFASWRIIHEGGIDPILRGLMATPAKLNRQDSMLVDELRDKLFQQVRRI- 552

  Fly  1115 FSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATNWNDLSREIPT-EVINRFQKIYASVDDIDL 1178
              |:||.|||:||:||||:|.||.:|..|.|.:..|...|||.:.. ::..:|.::|.:.|:||:
Mouse   553 --GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLYKTPDNIDI 615

  Fly  1179 FPGAMTERPLQGGLVGPTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVC 1243
            :.||:.|..|.|..|||.|||:...|||:.|..||||::...   .||:.|...:|:::|::|||
Mouse   616 WVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKWG---VFTKRQRKALRRISLSRIVC 677

  Fly  1244 ENLEIT---GDMQRAAFDLPSNFLNPRVPCASMPQIDLNAWR 1282
            :|..||   .|:.||.. .|..|    |.|:.:|:::|:|||
Mouse   678 DNTGITTVSRDIFRANI-YPQGF----VSCSRIPKLNLSAWR 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_609883.1	An_peroxidase	69..537	CDD:460804
		An_peroxidase	719..1257	CDD:460804	220/580 (38%)
Epx	NP_031972.2	myeloperoxidase_like	288..700	CDD:188656	170/429 (40%)