DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10211 and epx

DIOPT Version :9

Sequence 1:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster
Sequence 2:	XP_021326443.1	Gene:	epx / 100331172	ZFINID:	ZDB-GENE-130425-2	Length:	828	Species:	Danio rerio

Alignment Length:	834	Identity:	251/834 - (30%)
Similarity:	377/834 - (45%)	Gaps:	189/834 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   625 PDGTAASF------SKANLAALNLANSSLIFELTSNEIVKTLNHITRRKRQIFNPNQNAFNRNEL 683
            |:...|.|      :||::.|....::::  ||. .|:|.|                ::.::.:|
Zfish    10 PNDLLALFKQTGPKTKAHIRAAEFLDNTV--ELI-REMVYT----------------HSMDKPDL 55

  Fly   684 TDTLQTVDISGLLGGAQKQLDTC------PEPSQQCDANSPFRTLSGRCNN----LRNPNWGKSL 738
            ::.|...|:..:|     |...|      |.....| .:..:||::|.|||    ..||.||.:.
Zfish    56 SELLSAEDMETIL-----QATGCSAEMKRPVCKSDC-LSKRYRTITGHCNNSYFDRENPQWGAAN 114

  Fly   739 TTFSRLLPAQYEDGISAPR------------LTGVTGTALPNPRTISTTIHPDISNLHTR----- 786
            |.::|.|..||||...|||            |..|..||:||.|.:|..:      |:|:
Zfish   115 TPYARWLSPQYEDPRGAPRGWSPQHTYHNHTLPPVRLTAVPNVRRVSQEV------LYTQNGNIT 173

  Fly   787 ----YSLMVMQFAQFVDHDLTLT---PIHKGFHESIPSCRPCNSRQTVHPECNPFPVPAGDFYYP 844
                .|.:::::.|::|||||||   |....|.......|.|::    ...|.|..:|..|   |
Zfish   174 LDGSLSHLLVEWGQWIDHDLTLTPQSPSTAAFRTRADCTRTCST----DTPCFPIQIPLSD---P 231

  Fly   845 EVNVTSGERFCFPSMRSLPGQQS-LGPRDQINQNTHFLDGSMVYGETTCLSNKLRGFSGR----- 903
            ..:..|    |....||.|...| ||.|:|:|..|.|:|.|||||.:..|:..||..|..
Zfish   232 RSHTQS----CMAFFRSAPSCSSPLGQREQLNAITAFVDSSMVYGSSDALALSLRNLSSPLGLLA 292

  Fly   904 ---------------MNSTQVRGKELLPLGP-----HPECKSRN--------GLCFLGGDDRASE 940
                           :|.||   .:|.|.||     |.....:|        ..||..||.||:|
Zfish   293 VNQFHSDQGFDFMPFLNRTQ---PQLDPCGPRQHSDHTTAPQQNNNISMGNASFCFQAGDSRANE 354

  Fly   941 QPGLTAIHTAFLREHNRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVN 1005
            ..|:.|:||.|||||||:.:.|..:||||:.:.|:..||||:.|..|.:.::.:||.:|..:|..
Zfish   355 HLGMIALHTLFLREHNRLAKELHRINPHWSPDTLYQEARKILGAVHQILTWDHYLPHVLGRSANQ 419

  Fly  1006 LYGLKLLPQGYYKDYNPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQ--PVEPPLLLRDGF 1068
            :    |:|.  ||.|:|:..|.:.|.|:.||||..|..:.|.:.||...::  |..|.|.|....
Zfish   420 I----LMPA--YKGYDPAADPSISNIFSTAAFRFAHVTVHPVVNRLGPDYRLSPAHPALPLHHSL 478

  Fly  1069 FRMDALLQPGIIDEILRGLVATP--METLDQFITGEVTNHLFEDR-KIPFSGIDLIALNIQRARD 1130
            |....:::.|.||.:||||:.:|  ::|.||.:..|:|..||:.: .:|   :||.|||:||.||
Zfish   479 FASWRVVKEGGIDPVLRGLLVSPAKLQTADQMMVEELTERLFQAQGGLP---LDLAALNLQRGRD 540

  Fly  1131 HGIPSYNNYRALCNLKRATNWNDLSREI-PTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLVG 1194
            ||:..|:.:|.||.|....|.:.||..: .|.:..:...:|...::||::.||:.|..|.||.||
Zfish   541 HGLQGYSVWRELCGLPAPVNESALSGILGNTALARKLLDLYGVAENIDVWVGAIAEPALPGGRVG 605

  Fly  1195 PTLACIIGIQFRQLRKCDRFWYENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDL 1259
            |.|||:|..|||.||..||||::|   |..|:..|...:|..:|::|:|||..|    |:...|.
Zfish   606 PLLACLIARQFRGLRDGDRFWWQN---EGVFSSGQRDALRSTSLSRIICENTHI----QQVPLDP 663

  Fly  1260 PSNFLNPR--VPCASMPQIDLNAWRENVQGCQIGNRNVRVGESAFPSPCTSCVCSAEGAQCASLR 1322
            .:|.:.|.  :.|:::...:|:||.|                     |.:..||.|.
Zfish   664 FTNTMRPEELLSCSNIQLFNLSAWTE---------------------PDSDPVCGAV-------- 699

  Fly  1323 ITDCGQLIRQWPKEAILRDEVCNS----QC--GIYLTGQQASGFNPQQRQGQAQ 1370
                       |:..:....:|.|    ||  |..|.|......:||......|
Zfish   700 -----------PRLTLGFSVLCGSAVFYQCPAGFLLIGATHVTCDPQTHHWSPQ 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	205/593 (35%)
		peroxinectin_like	871..1245	CDD:188655	149/412 (36%)
epx	XP_021326443.1	An_peroxidase_like	111..689	CDD:326323	207/613 (34%)
		CCP	<711..747	CDD:153056	9/32 (28%)
		EGF_CA	748..>775	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920