DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and ATG26

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_013290.1	Gene:	ATG26 / 850886	SGDID:	S000004179	Length:	1198	Species:	Saccharomyces cerevisiae

Alignment Length:	506	Identity:	101/506 - (19%)
Similarity:	165/506 - (32%)	Gaps:	164/506 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISP 78
            :..|||..|:...:   .|:.|         ....|:::||.|..:.       |....:.:.|.
Yeast   740 YKFGLLTIGSRGDV---QPYIA---------LGKGLIKEGHQVVIIT-------HSEFRDFVESH 785

  Fly    79 --SFDIPKHFPKENIFSMQFVSDFNNLEL----------WWTIGLMTTEHAFKDPKVKKLIESKD 131
              .|:.....|.| :.|:...::..|:::          |....|.|:.......|...||||..
Yeast   786 GIQFEEIAGNPVE-LMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPS 849

  Fly   132 DHYDLVIIEQF---FHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWS---LIPHLLLSH 190
            ....:.|.|..   :..||.|                             ||:   ..||..:.
Yeast   850 AMVGIHITEALQIPYFRAFTM-----------------------------PWTRTRAYPHAFIV- 884

  Fly   191 TDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPL------------PNVLDL 243
            .|:...|.  || ||:               ..|.|..|...|.|.:            .|:..|
Yeast   885 PDQKRGGN--YN-YLT---------------HVLFENVFWKGISGQVNKWRVETLGLGKTNLFLL 931

  Fly   244 ERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQL---PTDLQNFLDNA-TYG--VIYFSM 302
            ::|....|.|...:|..|.......:.|.|......|..   |.:||.|:..| :.|  ::|...
Yeast   932 QQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFKPPAELQEFISEARSKGKKLVYIGF 996

  Fly   303 GSYVKSTDLPQEKTALILKAFGQLKQQVI----WKFENDSIG---------DLPSNVM-----IK 349
            ||.|.|.  .:|.|..:::|..:.....|    |   ::.:|         |||.|::     ..
Yeast   997 GSIVVSN--AKEMTEALVEAVMEADVYCILNKGW---SERLGDKAAKKTEVDLPRNILNIGNVPH 1056

  Fly   350 KWM-PQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQ--HRNTIKSVREGYA---- 407
            .|: ||.|...|        |||...|...:..|:|.:..|.:|||  :...::.:..|.|
Yeast  1057 DWLFPQVDAAVH--------HGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIALKKL 1113

  Fly   408 ---------------------RSLVFSKLTTDDLVRN-IETLINDPQYKRS 436
                                 ..|:..|::.:|.::. |..:.|:.:|.||
Yeast  1114 NAQTLADALKVATTNKIMKDRAGLIKKKISKEDGIKTAISAIYNELEYARS 1164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	101/506 (20%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	95/483 (20%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		YjiC	739..1168	CDD:224732	101/506 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000