DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt301D1 and UGT85A3

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_173655.2	Gene:	UGT85A3 / 838845	AraportID:	AT1G22380	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	105/516 - (20%)
Similarity:	172/516 - (33%)	Gaps:	173/516 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PFPAPSHWLWLEHFQNDLLR-------QGHHVTSVNNHPTKHPHENL------TEIIISPSF--- 80
            |:||..|       .|.:::       :|.|||.||   |.:.|..|      ..:...|||
plant    18 PYPAQGH-------INPMMKVAKLLHVKGFHVTFVN---TVYNHNRLLRSRGANALDGLPSFQFE 72

  Fly    81 DIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIEQFFHE 145
            .||...|:..:.:.|.:.         .:...||::..  ...|||::......|:..:
plant    73 SIPDGLPETGVDATQDIP---------ALSESTTKNCL--VPFKKLLQRIVTREDVPPV------ 120

  Fly   146 AFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLY-- 208
                     :| :|:.|:|.:..::...:|       :|.:....|....|     .|||..|
plant   121 ---------SC-IVSDGSMSFTLDVAEELG-------VPEIHFWTTSACGF-----MAYLHFYLF 163

  Fly   209 -------------------DAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLE---------R 245
                               |.|: .|:  |.|..:..|.....|....||.:.|.         :
plant   164 IEKGLCPVKDASCLTKEYLDTVI-DWI--PSMNNVKLKDIPSFIRTTNPNDIMLNFVVREACRTK 225

  Fly   246 NISLVLINA-----HRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQ------NFLDNAT----- 294
            ..|.:::|.     |..|...:..:|.:..:|..|:...:::..|.:      |.....|
plant   226 RASAIILNTFDDLEHDIIQSMQSILPPVYPIGPLHLLVNREIEEDSEIGRMGSNLWKEETECLGW 290

  Fly   295 ------YGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGD----LPSNV--- 346
                  ..|:|.:.||....|.....:.|..|.|.|   ::.:|....||:..    :|...
plant   291 LNTKSRNSVVYVNFGSITIMTTAQLLEFAWGLAATG---KEFLWVMRPDSVAGEEAVIPKEFLAE 352

  Fly   347 -----MIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKS----- 401
                 |:..|.||..:|:||.|..|:||.|...|.|.:..||||:|.|.:.:|..|...|
plant   353 TADRRMLTSWCPQEKVLSHPAVGGFLTHCGWNSTLESLSCGVPMVCWPFFAEQQTNCKFSCDEWE 417

  Fly   402 --------VREGYARSLV-------------------------FSKLTTDDLVRNIETLIN 429
                    |:.|...::|                         .:||.....|.|.||::|
plant   418 VGIEIGGDVKRGEVEAVVRELMDGEKGKKMREKAVEWRRLAEKATKLPCGSSVINFETIVN 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	105/516 (20%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	102/511 (20%)
UGT85A3	NP_173655.2	Glycosyltransferase_GTB_type	9..478	CDD:299143	104/514 (20%)
UGT85A3	NP_173655.2	MGT	20..459	CDD:273616	97/493 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050