Protein Alignment Ugt301D1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 538
• Identity: 160/538 - (29%)
• Similarity: 255/538 - (47%)
• Gaps: 68/538 - (12%)

  Fly    11 MLIFLIGLLEFGAGSRILFM-GPFPAPSHWLWLEHFQNDLLRQGHHVTSV--NNHPTKHPHENLT 72
            ::..|:..::.|...|:|.| |.:   |||..:......|:.:.|.||.:  ::.||. ||..
Zfish     7 LVCLLLCGVDVGWSGRVLVMPGEY---SHWHNMRAIIEALVDRNHSVTVLVSSSSPTV-PHTQ-- 65

  Fly    73 EIIISPSFDIPKHFPKENIFSMQ---FVSDFNNLELW--------------WTIGLMTTEHAFKD 120
                ...||.  |..|.|:...:   ..|||.:  ||              |.:  |:.......
Zfish    66 ----KARFDY--HVFKVNMDKEEAKVIWSDFTH--LWMKETDSKLERGFLIWRV--MSNFRRLAA 120

  Fly   121 PKVKKLIESKD-------DHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGIL- 177
            ...:.|:::.|       .|||::..:.....:.|| .:..|.|.|....:.:|...:...|.:
Zfish   121 DVCRSLLQNDDLLQMLGESHYDVLFSDPMMPCSDLM-AQTLNIPQVISLRLTFAYTFERMCGQMP 184

  Fly   178 TPWSLIPHLLLSH--TDRMTFGQRAYNAYL-SLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPN 239
            .|.|.:|.:.|:.  ||||:|.:|..|..| .::..|.|    |..|..:...|.:  |.|....
Zfish   185 APPSYVPAVALTDHLTDRMSFMERVENMLLYFIHTTVFR----LNTMLTVDRLYTE--IRGKPTT 243

  Fly   240 VLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNA-TYGVIYFSMG 303
            :.:......:.||..:...:.|||..|....|||.|.:..|.|..:::.|:.:: .:||:.||:|
Zfish   244 MCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLG 308

  Fly   304 SYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFIT 368
            |.:|  :|..|:...|..|.||:.|:|:|::...:...|..|..|..|:||||:|.||..|.|||
Zfish   309 SMIK--NLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFIT 371

  Fly   369 HGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQY 433
            |||..|..|.||.||||:.:||:.||..|.:....:|.|..|..:.|.:.|||..::|::|:|.|
Zfish   372 HGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSY 436

  Fly   434 KRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFL 498
            |.|.:.:|:...|.|:.|||:|.:|||:::|::||:||:.....:..:||..|||...||..|.|
Zfish   437 KESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAAL 501

  Fly   499 AIWLPWRMIRRVHKWWLK 516
            ..:|           |:|
Zfish   502 ITFL-----------WVK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	142/476 (30%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	158/524 (30%)