Protein Alignment Ugt301D1 and ugt2a5

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001070111.2
• Gene: ugt2a5 / 767705
• ZFINID: ZDB-GENE-060929-796
• Length: 532
• Species: Danio rerio
• Alignment Length: 557
• Identity: 158/557 - (28%)
• Similarity: 259/557 - (46%)
• Gaps: 71/557 - (12%)

  Fly    11 MLIFLIGLLEFGAGSRILFM-GPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEI 74
            ::..|:..::.|...|:|.| |.:   |||..:......|:.:.|.||                :
Zfish     7 LVCLLLCGVDVGWSGRVLVMPGEY---SHWHNMRPVIEALVDKNHSVT----------------V 52

  Fly    75 IISPSFDIPKHFPKE----NIFSMQFVSDFNNLELWWTIGLMTTEHAFKDP------KV-KKLIE 128
            ::..|.....|..||    ::|.:....:..:..:...|.|.|.:.|.|..      || .|.:|
Zfish    53 LVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFTNDTAAKYEGEFVMWKVMSKFVE 117

  Fly   129 -----------------SKDDHYDLVIIEQFFHEAFLMFGKRFNCP-VVTI-GTMGYADNIDHAM 174
                             .:|.:||::..:.....:.|| .::.|.| |::: .|..||  .:...
Zfish   118 FGDVYFRGLFDVGLLKTLRDSNYDVLFSDPMMPFSDLM-AQKLNIPQVISMRATFAYA--AERLC 179

  Fly   175 GIL-TPWSLIPHLLLSH--TDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGP 236
            |.: .|.|.:|.:.|:.  ||||:|.:|..|..|.:..::.     .|.:.......:...|.|.
Zfish   180 GQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYIVHSIA-----FPLVATFTFDGYYSEILGK 239

  Fly   237 LPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNA-TYGVIYF 300
            ...:.:....:.:.||..:...:.|||..|....|||.|.:..|.|..:|:.|:.:: .:||:.|
Zfish   240 PTTMCETMGKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKELEEFVQSSGDHGVVVF 304

  Fly   301 SMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKL 365
            |:||.:|  :|..|:...|..|.||:.|:|:|::...:...|..|..|..|:||||:|.||..|.
Zfish   305 SLGSMIK--NLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKA 367

  Fly   366 FITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLIND 430
            ||||||..|..|.||.||||:.:||:|||..|.:....:|.|..|....:.:.|||..::.::|:
Zfish   368 FITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNN 432

  Fly   431 PQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLL-- 493
            |.||.|.:.:|:...|.|:.|||:|.:|||:::|::||:||:.....:..:||..|||...||
Zfish   433 PSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSI 497

  Fly   494 --LGAFLAIWLPWRMIRRVHKWWLKGESSNKLNEGKK 528
              |..||.:.....:.||..:   |.....|..:.||
Zfish   498 TALITFLWVKACCFLFRRCVR---KTRPERKRQKNKK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	136/479 (28%)
ugt2a5	NP_001070111.2	UDPGT	21..519	CDD:278624	152/529 (29%)