Protein Alignment Ugt301D1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 567
• Identity: 157/567 - (27%)
• Similarity: 252/567 - (44%)
• Gaps: 118/567 - (20%)

  Fly     8 KCWM------LIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSV--NNHPT 64
            ||.:      |||:.....  ||:.::..|.:   |||..:.:..::||.:.|.||.:  :..||
Zfish     3 KCLLKPSPLVLIFIFSFTH--AGNVLVLPGEY---SHWQNMRNVVDELLNRNHTVTVLVCSASPT 62

  Fly    65 KH--PHENLTEIIISPSFDIPKHFPKENIFSMQFVSDFNN--LELWWTIGLMTTEHAFKDPKVKK 125
            .:  ..|....::    |::|        .|.|.:...:.  :.:|       |:|    |...:
Zfish    63 INFTQQERFQYLV----FEVP--------LSAQELDGASEELIHIW-------TQH----PSPNR 104

  Fly   126 LIESKDDHYDLVIIE-----QFFHEAF----------------LMFGKRFNCPVVTIGTMGYADN 169
            |..:      |.|||     :..|.|.                |.|...||.|:...     ||.
Zfish   105 LQTA------LQIIELLGRVRVMHRAMCDSMLRNDALIAQLSALKFDVLFNDPMFMC-----ADL 158

  Fly   170 IDHAMGI---------------------LTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAV-- 211
            :...:|:                     ..|.|.:|......||||.|.:|..|...::..:|
Zfish   159 LAEMLGLPLVLSVRISPGFCLERMCGQMPAPPSFVPITQTVLTDRMCFMERVQNMIANIVFSVSF 223

  Fly   212 -MRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAH 275
             :..|:.|       :.|:. .:.|....:.:......:.||..:...:.|||..|....|||.|
Zfish   224 YIVAWISL-------DSYYT-DVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLH 280

  Fly   276 IQKPKQLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSI 339
            .:..|.|..:::.|:.:: .:||:.||:||.:|  :|..|:...|..|.||:.|:|:|::...:.
Zfish   281 CKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIAAALGQIPQKVVWRYSGKTP 343

  Fly   340 GDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVRE 404
            ..|..|..|..|:||||:|.||..|.||||||..|..|.||.||||:.:||:.||..|.:....:
Zfish   344 ETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTK 408

  Fly   405 GYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGAR 469
            |.|..|..:.|.:.|||..::|::|:|.||.|.:.:|:...|.|:.|||:|.:|||:::|::||:
Zfish   409 GAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAK 473

  Fly   470 HLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLK 516
            ||:.....:..:||..|||...||..|.|..:|           |:|
Zfish   474 HLRVQAHELSWYQYHCLDVAAFLLSIAALITFL-----------WVK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	137/497 (28%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	151/545 (28%)