Protein Alignment Ugt301D1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 526
• Identity: 153/526 - (29%)
• Similarity: 250/526 - (47%)
• Gaps: 61/526 - (11%)

  Fly    11 MLIFLIGLLEFGAGSRILFMGPFPAP-SHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEI 74
            :|||.:.|.|......::.   :|.. ||||.::....:|:::.|.||.:....|...:..|...
Mouse     8 LLIFHLTLAEIVLSGNVVV---WPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAF 69

  Fly    75 IISPSF-DIPKHFPKENIFSM-------------------QFVSDFNN-LELWWTIGLMTTEHAF 118
            |   :| :||..:.|..|..:                   .|..:..| |..::|......:...
Mouse    70 I---NFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVL 131

  Fly   119 KDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGK----RFNCPVVTIGTMGYADNID-HAMGILT 178
            .:|.|.:.::.  ..:|:::.     :...|.|:    :...|.|.......|..:: |...|..
Mouse   132 NNPTVMERLQK--GGFDVLLA-----DPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPA 189

  Fly   179 PWSLIPHLLLSHTDRMTFGQRAYN--AYLSLYDAVMR----RWVYLPKMQKLAEKYFQGSIEGPL 237
            |.|.:|..|...||:|:||:|..|  :| ||.|.:.:    .|          ..|: ..:.|..
Mouse   190 PISYVPAALSELTDQMSFGERVKNIISY-SLQDYIFKTYWGEW----------NSYY-SKVLGRP 242

  Fly   238 PNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLD-NATYGVIYFS 301
            ..:.:......:.|:..:...:.|||.:|....|||.|.:..|.||.:::.|:. :..:|::.||
Mouse   243 TTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFS 307

  Fly   302 MGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLF 366
            :||.||  :|..||..||..|..|:.|:|:|:::......|.||..:..|:||||:|.||..:.|
Mouse   308 LGSMVK--NLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAF 370

  Fly   367 ITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDP 431
            |||||..|..|.||.|:||:.||::.||..|......:|.|..:..:.:|:.||:..:.|:||:|
Mouse   371 ITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEP 435

  Fly   432 QYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGA 496
            .||.:|:.:|:...|.|:.|||.|.||||:::||:||:||:.....:...||..|||:|.||...
Mouse   436 SYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACV 500

  Fly   497 FLAIWL 502
            ..||.|
Mouse   501 ASAILL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	136/478 (28%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	148/512 (29%)