DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and Ugt35E1

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	174/511 - (34%)
Similarity:	281/511 - (54%)	Gaps:	44/511 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LIFLIGLL--EFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEI 74
            |.:||.||  .|..|:|||.:.|.|:.||:.....:..:|...||.:|||:..|::.|.:|:.:|
  Fly     6 LFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDI 70

  Fly    75 IISP---SFD-------IPKH----FPKENIFSMQFVSD-FNNLELWWTIGLMTTEHAFKDPKVK 124
            .:..   |||       .||:    |...|.|......| |||                 |...:
  Fly    71 YVPEVLNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNN-----------------DGVRR 118

  Fly   125 KLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLI--PHLL 187
            :::......:||:|::.:.::||......|..|::.:...|....||..:|..:|.|.:  |...
  Fly   119 EILRPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSY 183

  Fly   188 LSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIE-GPLPNVLDLERNISLVL 251
            |.:.|  |||.|..:............|.|..|.:.|.:|||....| .||.   ::.::|:|||
  Fly   184 LYNLD--TFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLS---EISQDIALVL 243

  Fly   252 INAHRSIDLPRPSMPGLIDVGGAHI-QKPKQLPTDLQNFLD-NATYGVIYFSMGSYVKSTDLPQE 314
            :|.|.::..|||.:|.:|:|||.|| ::||.|..||::|:. :..:||||||:|:.|::.::..:
  Fly   244 VNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDD 308

  Fly   315 KTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGI 379
            :..::::|||.|.|:|:||||::.:.|:||||:::||:||.|:||||.|||||||||:..|.|.|
  Fly   309 RKRILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESI 373

  Fly   380 YWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRF 444
            ::|.|||.:|.:.||..|.....:.|:..||.:..:|:|:|...|..|:.:.:::.:|.....|:
  Fly   374 HYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARY 438

  Fly   445 RDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAI 500
            ||.|:.||:.|.:|..|::||:||.|::..|..:....:..|||||.:||...|.|
  Fly   439 RDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	165/492 (34%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	153/465 (33%)
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	161/476 (34%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	156/472 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860