DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt301D1 and Ugt302K1

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	169/522 - (32%)
Similarity:	269/522 - (51%)	Gaps:	32/522 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 MLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEII 75
            :::.|:..|.:.:|...|.:......||:.........|::.||.:|.|:..|.|.|....|::.
  Fly     6 LILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVS 70

  Fly    76 ISPSFD------------IPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIE 128
            :....:            |.|.:.:             ||...:.:|...|...|:|...:..::
  Fly    71 VPNVIEVMGGDIGALWASIQKTYTQ-------------NLIDHYQMGFRITRGLFEDSNFQDFLK 122

  Fly   129 SKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDR 193
            | :..:|.:|.|.|:::|.....:.||.|::.:.|.|....|...:|...|.|.:||::|...|.
  Fly   123 S-NQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDH 186

  Fly   194 MTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSI 258
            |:..:|..|.....|:.|:..:.:||..:||.:::|.|:..    ....:.||.||||||.|.|:
  Fly   187 MSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKR----CFYKMRRNASLVLINQHVSL 247

  Fly   259 DLPRPSMPGLIDVGGAHIQ-KPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKA 322
            ..|||..|.:|:|||.||. |...||..::.|::.:.:|.|||||||.:|:.|||..|...||||
  Fly   248 SFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKA 312

  Fly   323 FGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLC 387
            .|.|||:|:||||.|::.:.|.||.|..|.||.||||||.:..|:||||:..|.|.||...|::.
  Fly   313 LGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIG 377

  Fly   388 VPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPL 452
            :|::.||..|...:.:.||...|.|..|...:..:.||.:.::|.|.:....:|.|:||....|:
  Fly   378 LPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPI 442

  Fly   453 DEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCL-LLGAFLAIWLPWRMIRRVHKWWLK 516
            :.|.:|:|::.||:||.:|||....:...||..:|||..: ::...|.|.||..:.:.:.|..||
  Fly   443 ENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLK 507

  Fly   517 GE 518
            ||
  Fly   508 GE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	155/483 (32%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	151/458 (33%)
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	159/491 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860