Protein Alignment Ugt301D1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 551
• Identity: 154/551 - (27%)
• Similarity: 258/551 - (46%)
• Gaps: 88/551 - (15%)

  Fly    15 LIGLLEFGA-----GSRILFMGPFP-APSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTE 73
            |:|||...|     |.::|.   || ..||||.:.....:|..|||..
Mouse    10 LVGLLLLCALPWTEGEKVLV---FPVGGSHWLSMRDVVRELHAQGHQT----------------- 54

  Fly    74 IIISPSFDIPKHFPKENIFS----------MQFVSDFNNLELWWTIG-----LMTTEHAFKDPKV 123
            ::::|  ::.....:|:.|:          .:......||::::..|     :..|..|.::...
Mouse    55 VVLAP--EVNMRIKEEDFFTFKVYAVPYTRQELEEMMENLKVFFDTGNYMKKIFKTSEALRNMST 117

  Fly   124 KKL--------IESKDDH-----YDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYAD-NIDH-A 173
            ..|        .||...|     :|:|..:..|....|: .|....|.|..  :.|.. .|:: |
Mouse   118 VLLKTCTNILHNESLLHHLNSSSFDVVFTDPVFPCGALL-AKYLGIPAVFF--LRYIPCGIEYEA 179

  Fly   174 MGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYL--PKMQKLAEKYFQGSIEGP 236
            ....:|.|.||:|....:|.|.|.||..|   .||..|::...:|  ...:.||.:.||..:..
Mouse   180 TQCPSPSSYIPNLFTRLSDHMDFLQRVQN---MLYHLVLKYICHLLITPYESLASELFQREVSS- 240

  Fly   237 LPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLD-NATYGVIYF 300
                ::|....|:.|......:|.|||.||.::.:||.:....|.|..:.:.::: :..:|::.|
Mouse   241 ----VELFSYASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEHGIVVF 301

  Fly   301 SMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKL 365
            |:||.|  :::|::|...|.:|.|::.|.|:|::......:|..|.::.||:||||:|.||..:.
Mouse   302 SLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRA 364

  Fly   366 FITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLIND 430
            ||||.|..|..|||..||||:.:||:|||..|..:....|...:|...::|.|||...::|:||:
Mouse   365 FITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN 429

  Fly   431 PQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLG 495
            ..||.:.:.:|...:|.||.|||.|.||:||::||:||.||:.....:..:||..|||:|.||..
Mouse   430 KSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAI 494

  Fly   496 AFLAIWLPWR--------------MIRRVHK 512
            ....:::.::              .:::.||
Mouse   495 VLTVVFIVFKCCAYGCRKCFGGKGRVKKSHK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	135/478 (28%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	146/528 (28%)