Protein Alignment Ugt301D1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 158/531 - (29%)
• Similarity: 262/531 - (49%)
• Gaps: 44/531 - (8%)

  Fly     9 CWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHE--NL 71
            |..|....|   |....|:|.: |... |||..::.....|..:||.|..|....:.|..:  |.
  Rat    13 CVCLFLASG---FAQAGRLLVV-PMDG-SHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNF 72

  Fly    72 TEIIISPSF---DIPKHFP--KENIFSMQFVSDFNNLEL----WWTIGLMTTEHAFKDPKVKKLI 127
            |....|.|:   |:..||.  ..|.:..|.|..|:.|:.    ::.:........|||   |||:
  Rat    73 TVKTYSVSYTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKD---KKLV 134

  Fly   128 E-SKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHT 191
            | .|...:|.|.::. |....|:..|.|:.|.|......:...:|......:|.|.:|.:|...|
  Rat   135 EYLKQSSFDAVFLDP-FDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFT 198

  Fly   192 DRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHR 256
            |.|||.:|.:| :||    .|:...:.|...|.|.:.....::.|: .:.||...:|:.:.....
  Rat   199 DTMTFKERVWN-HLS----YMKERAFCPYFFKTAVEIASEVLQTPV-TMRDLFSPVSIWMFRTDF 257

  Fly   257 SIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLD-NATYGVIYFSMGSYVKSTDLPQEKTALIL 320
            .::.|||.||.::.:||.:..:.|.|..:.:.::: :..:|::.||:||.|  :::|::|...|.
  Rat   258 VLEFPRPVMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIA 320

  Fly   321 KAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPM 385
            :|.|::.|.|:|::......:|..|.::.||:||||:|.||..:.||||.|..|..|||..||||
  Rat   321 EALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPM 385

  Fly   386 LCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIH 450
            :.:||:|||..|..:....|...:|...::|.|||...::|:||:..||.:.:.:|...:|.||.
  Rat   386 VMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIE 450

  Fly   451 PLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWR---------- 505
            |||.|.||:||::||:||.||:.....:..:||..|||:|.||......:::.::
  Rat   451 PLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCF 515

  Fly   506 ----MIRRVHK 512
                .:::.||
  Rat   516 GGKGRVKKSHK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	141/458 (31%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	152/508 (30%)