Protein Alignment Ugt301D1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 170/541 - (31%)
• Similarity: 259/541 - (47%)
• Gaps: 88/541 - (16%)

  Fly     1 MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAP-SHWLWLEHFQNDLLRQGHHVT------S 58
            |.|: |...::||.||.....||..::|.   :|.. |||:.::...|:|.::||.||      |
  Rat     1 MSMK-QTSVFLLIQLICYFRPGACGKVLV---WPTEYSHWINIKIILNELAQRGHEVTVLVSSAS 61

  Fly    59 VNNHPTKHPHENLTEIIISP--SFDIPKHFPKENIFSMQFVSDFNNLELW--------------- 106
            :...|||....|. ||...|  ..|:...|.|   :..::..||..|.:|
  Rat    62 ILIEPTKESSINF-EIYSVPLSKSDLEYSFAK---WIDEWTRDFETLSIWTYYSKMQKVFNEYSD 122

  Fly   107 ----------WTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIE------QFFHEAF---LMFGK 152
                      |...||           |||   :...:|:::.:      :...|..   |::..
  Rat   123 VVENLCKALIWNKSLM-----------KKL---QGSQFDVILADAVGPCGELLAELLKTPLVYSL 173

  Fly   153 RFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVY 217
            || ||       ||... ..:.|:..|.|.:|.:|...:|||||.:|..|....||   ...|
  Rat   174 RF-CP-------GYRCE-KFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLY---FDFW-- 224

  Fly   218 LPKMQKLAEK---YFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKP 279
               .|...||   .|...:.|....:.::.....:.||.....::.|.|.:|....|||.|.:..
  Rat   225 ---FQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPA 286

  Fly   280 KQLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLP 343
            |.||.:::.|:.:: .:||:.||:||.||  :|.:||..::..|..|:.|:|:|:|:......|.
  Rat   287 KPLPREMEEFVQSSGEHGVVVFSLGSMVK--NLTEEKANVVASALAQIPQKVVWRFDGKKPDTLG 349

  Fly   344 SNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYAR 408
            ||..:.||:||||:|.||..|.|:.|||..|..|.||.|:|::.:||:.||..|....|.:|.|.
  Rat   350 SNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAV 414

  Fly   409 SLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKS 473
            .:.||.|:|..|:..::.::|||.||.:|:.:|:...|.|:.|||.|.|||||::||:||:||:|
  Rat   415 RVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRS 479

  Fly   474 HGAFIPLHQYLLLDVLGCLLL 494
            ....:...||..|||:|.|||
  Rat   480 TLHDLSWFQYHSLDVIGFLLL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	150/491 (31%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	161/517 (31%)