DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	531	Identity:	119/531 - (22%)
Similarity:	215/531 - (40%)	Gaps:	89/531 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPT---KH---PHENL 71
            :.::.|:........|...|....||..:.....:.|...||:||...  ||   |:   .:..|
Worm     5 LVILSLIYSTYSYNFLVFCPLFGHSHTKFFATIADALTDAGHNVTFFT--PTIVEKYRNVSYTKL 67

  Fly    72 TEIIISPSFDIPKHFPKENIFSMQFVS-DFNNLELWWTIGLMTTEHAFKDP----------KVKK 125
            |:.::  ..|.||...:   :..|..| ||:.   :|     |.:.:|.:.          ::..
Worm    68 TKDVV--HMDAPKKLME---YGEQMESADFSR---FW-----TEDSSFYNVGAADLYRCSIRLNG 119

  Fly   126 LIESKDDHYDLVIIEQFF------HEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIP 184
            |.:|..|:.:   |:.|.      |:.:|  .|....||:.                    |::.
Worm   120 LFKSLMDYLN---IKTFIPSLSLTHDVYL--SKAIGEPVMP--------------------SVVS 159

  Fly   185 HLLLSHTDRMTFGQRAYNAYLSLY-DAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNIS 248
            .:.....|:::..:||:||:...| |.|:.    .|....|:..|.:..|.       .:|...|
Worm   160 DVCSPFGDKLSLLERAFNAFAVPYIDIVLG----YPVHNTLSAPYTEIDIR-------TIEPEAS 213

  Fly   249 LVLINAHRSIDLPRPSMPGLIDVGGAHIQ----KPKQLPTDLQNFLDNATYGVIYFSMGSYVKST 309
            .:.:|::..:|.|||::...:::||..:.    |.:||.:...:.| |.....:..|.||...|.
Worm   214 FLFLNSNPFLDFPRPTLTKTVEIGGITVDLNQLKSQQLDSKWSDIL-NLREKTMLVSFGSVFFSK 277

  Fly   310 DLPQEKTALILKAFGQLKQ-QVIWKFENDSIGDLP---SNVMIKKWMPQNDILAHPNVKLFITHG 370
            |:|.|...:|..:..:.|. ..|||:|.:.|.|..   .|:...||:||..:||:..:..|.||.
Worm   278 DMPLENKKVIANSMTEFKNVTFIWKYEGNDIEDFARGIQNIHFVKWVPQTALLANRRLSAFFTHA 342

  Fly   371 GIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKL---TTDDLVRNIETLINDPQ 432
            |:....|..|.|.|.:..||:.||.||....||  :..|:..||.   .:..::...:.::.|..
Worm   343 GLGSINEVSYLGKPSILCPLFADQMRNAKMLVR--HNGSIELSKYDLGNSKKIIEAFQAILFDSS 405

  Fly   433 YKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAF 497
            |..:|.:::::..:.||.|........|:..|......|..:...:...:|.||||....:|...
Worm   406 YAENAQKLAEQLENQPIKPEKMMVKHAEFAARFGRLPSLDPYSRKMSFVEYFLLDVATICVLVLA 470

  Fly   498 LAIWLPWRMIR 508
            ..:::..|:::
Worm   471 CVVFVLTRVVQ 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	112/504 (22%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	109/480 (23%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	116/507 (23%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	65/248 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810