Protein Alignment Ugt301D1 and Ugt2b36

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001025038.1
• Gene: Ugt2b36 / 231396
• MGIID: 3576103
• Length: 530
• Species: Mus musculus
• Alignment Length: 574
• Identity: 168/574 - (29%)
• Similarity: 277/574 - (48%)
• Gaps: 101/574 - (17%)

  Fly     7 WKCWMLIFLIGLLEFGAGSRILFMGP---FPAP-SHWLWLEHFQNDLLRQGHHV------TSVNN 61
            || |:...|  ||:.....|....|.   :|.. |||:.::...::|.::||.|      ||:..
Mouse     3 WK-WISALL--LLQISCCFRSAKCGKVLVWPVDYSHWMNIKIILDELKQKGHEVTVLRPSTSIFL 64

  Fly    62 HPTKHP-----------HENLTEIIISP-----SFDIPK-----HFP-KENIFSMQFVSDF---- 100
            .|.|.|           ..::.|||.:.     ::::|:     :.| .:|||..  .||:
Mouse    65 DPKKSPGLKFETFPTSFSNDVMEIIFAKAVERWTYEVPRDTCLSYSPLLQNIFDE--YSDYCLTL 127

  Fly   101 -----NNLELWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLV----------IIEQFFHEAFLMF 150
                 :|.:|                 :.||.|||   :|::          :|.:.....|| :
Mouse   128 CKDTVSNKQL-----------------MAKLQESK---FDVILSDAIGPCGELIAELLQIPFL-Y 171

  Fly   151 GKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRW 215
            ..||        :.||... .::.|:..|.|.:|.:|...:.:|||.:|..|....||   ...|
Mouse   172 SLRF--------SPGYYLE-KYSGGLPLPPSYVPVILSGLSGQMTFKERVKNMICMLY---FDFW 224

  Fly   216 VYLPKMQKLAEK---YFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQ 277
                 .|...||   .|.....|....:::......:.||.::..::.|.|::|.:..|||.|.:
Mouse   225 -----FQTFREKKWDQFYSETLGRPTTLIETMGKAEMWLIRSYWDLEFPHPTLPNVYYVGGVHCK 284

  Fly   278 KPKQLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGD 341
            ..|.||.::::|:.:: .:||:.||:||.|  :::.:||...|..|..|:.|:|:|:|:..:...
Mouse   285 PAKPLPKEMEDFVQSSGEHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWRFDGKTPAT 347

  Fly   342 LPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGY 406
            |..|..|.||:||||:|.||..|.||||||..|..|.|:.|:||:.:||:|:||.|....|.:|.
Mouse   348 LGPNTRIYKWLPQNDLLGHPKTKAFITHGGANGLYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGA 412

  Fly   407 ARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHL 471
            |.:|....::..||:..:|.:|::|.||.:|:.:|....|.|:.|||.|.||||:::||:||:||
Mouse   413 AVTLNIRTMSRSDLLNALEEVIDNPFYKENAMWLSTIHHDQPMKPLDRAVFWIEFVMRHKGAKHL 477

  Fly   472 KSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLKGESSNKLNE 525
            :.....:..:||..|||:|.||......:.|..:....|:::::|.|...| ||
Mouse   478 RPLAYNLTWYQYHSLDVIGFLLAFVTFIVALIVKCFLFVYRFFVKKEKKMK-NE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	144/496 (29%)
Ugt2b36	NP_001025038.1	UDPGT	24..527	CDD:278624	158/544 (29%)