DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and ugt-59

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_501911.1	Gene:	ugt-59 / 187799	WormBaseID:	WBGene00011238	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	131/532 - (24%)
Similarity:	215/532 - (40%)	Gaps:	106/532 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ILFMGPFPAPSHWLWLEHFQNDLLRQGHHVT------------------SVNNHPTKHPHENLTE 73
            |||..|..:.||..:.......|...||.||                  :|.......|..:|.:
Worm    23 ILFYVPTLSHSHISFNTKLAQLLATSGHQVTVLLAQVDDALLIENATDFAVLRKKVGVPRGHLRQ 87

  Fly    74 IIIS---PSFDI----PKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKD 131
            ::.|   |..|.    |:.|.|....|..||:...|         |..:|.|       |...:.
Worm    88 VLWSNPGPYEDSSPLNPRIFYKLLKVSGTFVTACQN---------MAFDHLF-------LSSLQQ 136

  Fly   132 DHYDLVIIEQFFHEAFLMFGKRFNCPVVTIG---------TMGYADNIDHAMGILTPWSLIPHLL 187
            ..:|:.::||:....|.:|        .:||         |..|....: |:|:..|:|.:|.|.
Worm   137 QKFDVGLVEQYDSCGFGIF--------KSIGIENTVWLSATAIYRPQAE-ALGVHLPYSYVPELF 192

  Fly   188 LSHTDRMTFGQRAYNAYLS-----LYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNI 247
            ...:|:|:|.|:..|..:.     :.|..::.              ||..|.|....:..:.:..
Worm   193 AHFSDKMSFFQKVINILIGQATSFVLDVFVQG--------------FQSRIFGFEQGLGAISQET 243

  Fly   248 SLVLINAHRSIDLPRPSMPGLIDVGGAHIQK-PKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDL 311
            |.||||:....|...|......::||..:.| .|:|....|:..|:|..|.:..|.|...::.|:
Worm   244 SSVLINSVPFFDYSMPVSHQFSNIGGITVDKRDKKLDPYWQSIADSAENGFVLVSFGGIARTVDM 308

  Fly   312 PQEKTALILKAFGQLKQ-QVIWKFE--NDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIF 373
            .:....:...:|.:... ..|.|:|  ::|...:|.||::..|:||..::||.|.|..|||||..
Worm   309 TESMQRIFYDSFARFSHITFIVKYETSSNSTISVPDNVILTPWIPQLPLMAHKNYKTIITHGGWS 373

  Fly   374 GTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSAL 438
            ...|......||:.:||:.|..:|:..:..:|.|..|...:|:...:|..|.|::.:|:|.::..
Worm   374 SILETTMHSKPMILMPLFADHAKNSKVAESKGVAVLLDKMRLSRRRVVHAIYTILTNPKYTQNCE 438

  Fly   439 EVSQRFRDNPIHPLDEATFWIEYIIRHRG-------ARHLKSHGAFIPLHQYLLLDVLGCLLLGA 496
            :.|:.|.|.|| |.:|.   ||:.||...       |:||:...   |...||   .||.|::.|
Worm   439 KFSRMFSDTPI-PHEEL---IEWRIRQAAKPSRKAFAKHLRPKE---PDFSYL---KLGFLIIPA 493

  Fly   497 FL-------AIW 501
            .:       :||
Worm   494 MILYAKHGFSIW 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	123/505 (24%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	119/495 (24%)
ugt-59	NP_501911.1	UDPGT	33..490	CDD:278624	123/505 (24%)
ugt-59	NP_501911.1	Glycosyltransferase_GTB_type	<247..492	CDD:299143	73/254 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6953
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860