DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt301D1 and ugt-13

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_504317.2	Gene:	ugt-13 / 186766	WormBaseID:	WBGene00019232	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	548	Identity:	135/548 - (24%)
Similarity:	223/548 - (40%)	Gaps:	93/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDI 82
            |:.|.:...||...|....||..::......:...||:||....:....|  |:..::.:.:..|
Worm    11 LISFVSSKNILIYDPIFGFSHVKFVSLMAEIIANHGHNVTLFRPYHIALP--NVDGLVKNKNIQI 73

  Fly    83 PKHFPKENIFSMQFVSDFNNLELWWTIGLM--------------------TTEHAFKDPKVKKLI 127
            ..:|||.  :.....::......:|...|:                    |.....:|.:|...:
Worm    74 IDYFPKH--YDELLHAEKQTFPGFWNDPLISQPVLRSLVVSKLISGEMKRTATQLLQDERVLNEL 136

  Fly   128 ESKDDHYDLVIIEQF-FHEAFLMFGKRFNC----PVVTIGTMGYADNIDHAMGILTPWSLIPHLL 187
            .||  .:|:||.|.| ....:|.......|    |.|....:||         :|...|||.: .
Worm   137 RSK--KFDVVISETFEITGLYLAHIIDVPCIPMMPAVRYLDLGY---------LLGQPSLIGY-A 189

  Fly   188 LSHTDRMT----FGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEG----PLPNVLDLE 244
            .....:|.    |..|..:.|...:.:....|         ..:|...:||.    ||||..||.
Worm   190 QQPGSKMAPEAGFLDRLNDVYQYFFMSCETDW---------TSQYQNDNIEAAIGRPLPNWKDLL 245

  Fly   245 RNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPK-----QLPTDLQNFLDNATYGVIYFSMGS 304
            ||..:.::|::..:|...|:...::.|||..:...|     :|..:.:..|....|.|: .|.||
Worm   246 RNSPIYILNSNPYLDFAVPTTATIVQVGGMTVDLKKMKNVAKLSEEYETILAERDYAVL-ISFGS 309

  Fly   305 YVKSTDLPQEKTALILKAFGQLKQ-QVIWKFENDSIGD------LPSNVMIKKWMPQNDILAHPN 362
            .::|..:|......::|.|..|.. ..|||:|.   ||      ||.||.:|||:||..:||...
Worm   310 VIRSFQMPDNFKVGLIKLFESLSDVTFIWKYEK---GDVEFQKRLPKNVHLKKWVPQPSLLADKR 371

  Fly   363 VKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKL---TTDDLVRNI 424
            ||||:||||:..|.|..|.|.|.|.||::|||..|.....|.|.|  :.:||.   ..:.|...:
Worm   372 VKLFVTHGGLGSTTEVAYTGKPALMVPIFGDQPNNADMLARHGGA--IAYSKFDLANGEKLANTV 434

  Fly   425 ETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIP-------LHQ 482
            :.::.:|:||..|..:.....:.||.|.:.....:|:      |....:|.:.:|       :.|
Worm   435 KDMVFNPKYKEKAELLFDVLSNQPIDPKENFIKHLEF------AMKFPNHRSQVPAVNQAGLIAQ 493

  Fly   483 YLLLDVLGCLLLGAFLAIWLPWRMIRRV 510
            | .|||:...::.:.::.:|.:..:.|:
Worm   494 Y-YLDVIVFFVMISLISSYLSFVALCRL 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	128/519 (25%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	123/500 (25%)
ugt-13	NP_504317.2	egt	1..509	CDD:223071	133/535 (25%)
ugt-13	NP_504317.2	UDPGT	29..514	CDD:278624	129/522 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810