DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and ugt-63

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_504369.1	Gene:	ugt-63 / 182223	WormBaseID:	WBGene00015449	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	111/523 - (21%)
Similarity:	205/523 - (39%)	Gaps:	106/523 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LLRQGH-HVTSVN---------NHPT-------------------------KHPHENLTEIIISP 78
            ::.||. |.||:|         ||.|                         ::|.|       ||
Worm    31 VMDQGRSHATSINTFMHRLQKDNHTTALEFAHFRQDIDFGMDERFIDMSGFQNPFE-------SP 88

  Fly    79 SFDIPKHFPKENIFSMQFVSDFNNLE--LWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIEQ 141
            .||           .:.|..|::.:.  :.:..|..|..:..|..: ::..|...:.:|:.:.:.
Worm    89 DFD-----------KIAFEEDYSFIHQAVAYGFGSQTCNNILKHRR-ERFFEILYEDWDIYLSDS 141

  Fly   142 FFHEAFLMFGKRFNCPVVTIG----TMGYADNIDHAMGILTPWSL---------IPHLLLSHTDR 193
            .|  |...:|      :..|.    .|.::.:::.|.|....:|.         :|..:|::|
Worm   142 LF--AICGYG------MAEISGKPHVMMHSTDLEAAQGSFKGFSRNYATFVPSNLPFSMLNYT-- 196

  Fly   194 MTFGQRAYNAYLSLYDAVMRRW----VYLPKMQKLAEKYFQGSIEGPLP--NVLDLERNISLVLI 252
               ....|:...:.||     |    ::...:...|:|:...||. |.|  :..:..|..|....
Worm   197 ---VSNYYHRVWAAYD-----WFGSFIFTAYVGNFAQKWALRSII-PFPYFSFAEYNRRSSFTFT 252

  Fly   253 NAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDN-ATYGVIYFSMGSYVKSTDLPQEKT 316
            :...|:..|..........|....:..|.|..:.:.|::: .:.|.|..:.|:::.....|:...
Worm   253 DMPDSLFPPASRTNDFFSFGAYCKESSKPLDLEFKTFIEHPKSKGTILIAFGTFIDWRKAPKNYY 317

  Fly   317 ALILKAFGQLKQ-QVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIY 380
            ........:|.: ::||..:.:....|..:|....|:|||.||.|....||::|||:..|:|.|.
Worm   318 DAFATVVNRLSEYRIIWSMKGERPPGLKKHVKTSSWVPQNQILHHNKTVLFLSHGGLKSTKEVIC 382

  Fly   381 WGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFR 445
            ...|.:.||::|:|.||......:|:||.:...|:..|:|..::..::..|.|:::|.:....:.
Worm   383 SATPTIFVPMFGEQTRNAWLIKEKGFARIMNKFKINVDELDTHMREVLEHPNYQQNANKFLTYYM 447

  Fly   446 DNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQY-LLLDVLGCLLLGAFLAIWLPWRMIRR 509
            |.||..|||..|....:::         :|..:|.|.| ..||:....:|...|.|.:|..|:..
Worm   448 DQPIPTLDEGAFKFNRLVK---------YGGKMPSHFYPKSLDLSYFTVLNVDLLIVVPIMMLYL 503

  Fly   510 VHK 512
            |.|
Worm   504 VLK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	101/491 (21%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	101/491 (21%)
ugt-63	NP_504369.1	Glycosyltransferase_GTB_type	<276..500	CDD:299143	60/232 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010