DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt301D1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	572	Identity:	137/572 - (23%)
Similarity:	229/572 - (40%)	Gaps:	125/572 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIII 76
            |:.::.::...:...||...|....||..::....|.:...||:||..  .|.....:|...:|.
Worm     6 LLSILLVISLVSCKNILVYNPIFGYSHAKFVSQLANIIADHGHNVTVF--QPFHIALKNTDGLIK 68

  Fly    77 SPSFDIPKHFP---------KENIFSMQFVSDFNNLELWWTIGLM-------------------- 112
            :.:.:|..::|         |...|     .||      |...||
Worm    69 NKNIEIINYYPDHYAELLKKKTPTF-----PDF------WDSHLMNNPVLSSFLMPKALGGEFEQ 122

  Fly   113 TTEHAFKDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGIL 177
            ||...|:|.|:  |.:.|:.::|:::.|.|....|.:                 ||.::
Worm   123 TTTQLFQDQKI--LNDLKNRNFDVLLAETFEIAGFYI-----------------ADLLE------ 162

  Fly   178 TPWSLIPHLLLSHTDRM-----TFGQRAYNAYL-SLYDAVMRRWVYLPKMQKLAEKYF------- 229
                 ||.:.|....|:     .|||.:...|. ..|..|.....:|.::..|...:|
Worm   163 -----IPSIPLMSAVRLPIIDSAFGQPSILGYFPQQYSKVAPEAGFLDRLNDLYRIFFWNLTTQR 222

  Fly   230 ---------QGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQ---- 281
                     |.:|..|:|:..||.:...:.:.|::..:|...|:...::.|||..|...|.
Worm   223 LCQFQNDFIQKAIGHPVPHWRDLVKESPIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVA 287

  Fly   282 -LPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQ-QVIWKFENDSI---GD 341
             |..:.:|.|.... ..::.|.||.::|.::|....|.|:|.|..|.. ..|||:|.|.:   ..
Worm   288 ALTEEYENILAERE-STVFISFGSVIRSYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNR 351

  Fly   342 LPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGY 406
            ||.||.:|||:||..:||...||||:||||:..|.|..|.|.|.|.||::|||..|.....|.|.
Worm   352 LPKNVHLKKWVPQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHGG 416

  Fly   407 ARSLVFSKLTTDD---LVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGA 468
            |  :.:.|....|   |.:.:..::.:.:|:.:|.|:.:.....||.|.......:|:      |
Worm   417 A--VAYDKFDLADGEKLTKTVRDMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEF------A 473

  Fly   469 RHLKSHGAFIP--------LHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHK 512
            .....|.:.:|        .|.|  |||:|.|.|.:...:::.::::..:.|
Worm   474 MEFPKHRSQVPAINRTGLIAHYY--LDVIGVLTLASIFGLFVIFKILNILRK 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	129/541 (24%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	125/516 (24%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	122/487 (25%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	133/548 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810