DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt301D1 and ugt-60

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001021158.1	Gene:	ugt-60 / 176366	WormBaseID:	WBGene00007402	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	521	Identity:	147/521 - (28%)
Similarity:	226/521 - (43%)	Gaps:	81/521 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RILFMGPFPAPSHWLWLEHFQNDLLRQGHHV------------TSVNNHPTKHPHENLTEIIISP 78
            |||.:.|....||.|:.......|...||.|            |..|..|     |.::|
Worm    17 RILQIVPGFTNSHVLFNYRLAETLRFLGHDVKMWTQMEMAMLDTGNNKLP-----EGVSE----- 71

  Fly    79 SFDIPKHFPKE------NIF-SMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIES------- 129
             :.||.||...      .:| ||.|.|. :..:|||      |...|||.:|:...:.
Worm    72 -YRIPIHFTDTLKTEGLKVFQSMMFESG-DAHDLWW------TGQEFKDMRVEACEQMLRHDESV 128

  Fly   130 ----KDDHYDLVIIEQFFHEAF-LMFGKRFNCPVV---TIGTMGYADNIDHAMGILTPWSLIPHL 186
                :.|.:|:.|..  ||:.. |...|:.|...|   |.||..|..:... :|:.|..|.|||.
Worm   129 YEDFRKDGFDVAIAH--FHDLCPLAIAKKMNVKRVIWITHGTSIYEFSAVQ-LGLRTIPSTIPHP 190

  Fly   187 LLSHTDRMTFGQRAYNA--YLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEG-PLPNVLDLER-NI 247
            |.|......|..|..|.  :|||.|     :|.||:...:.|..|.....| ...::.||.: .:
Worm   191 LSSAGFSQLFLDRVQNTLWHLSLLD-----FVNLPQNLLVDENLFYREFVGADQDDLWDLAKTTV 250

  Fly   248 SLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTD--LQNFLDNATYGVIYFSMGSYVKSTD 310
            ..:|||..|.:|.|||....:...|...:.|.|:|..:  |::.::..:.|:|.||:|:...:|:
Worm   251 PSLLINGDRMLDFPRPLPIHIAFSGELGVSKGKKLVMEKWLEDIIEKPSDGLIVFSLGTVSNTTN 315

  Fly   311 LPQEKTALILKAFGQLK-QQVIWKFENDSIG-DLPSNVMIKKWMPQNDILAHPNVKLFITHGGIF 373
            :|.:.....|.|||:|| ..::|:.|....| :...|:.:.||:||.||:.||.:||.|.|||..
Worm   316 MPAQMINSFLGAFGKLKTYTILWRMEKSVAGAEKYENLHLVKWLPQKDIMRHPKMKLMIAHGGYN 380

  Fly   374 GTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLIND---PQYKR 435
            ...|....|:|.:.:||:.||..|..::.|  |..:.|..||  |..:.|:...|.:   |:|..
Worm   381 SFLEAAQAGIPAVLMPLFADQKINAKRAQR--YGMATVLDKL--DLTINNVYGAIKEALKPEYST 441

  Fly   436 SALEVSQRFRDNPIH-PLDEATFWIEYIIRHRGARH-LKS-HGAFIPLHQYLLLDVLGCLLLGAF 497
            :|.::|....|.... |.....:.::.....:.:.. ||| |.:|:..|.   ||:...:||.||
Worm   442 NAKKLSAMLSDQVARKPYSALRYSLKLATSPKPSLFTLKSQHLSFLEFHN---LDIFSIVLLTAF 503

  Fly   498 L 498
            :
Worm   504 I 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	141/504 (28%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	137/493 (28%)
ugt-60	NP_001021158.1	Glycosyltransferase_GTB_type	17..>161	CDD:299143	41/163 (25%)
ugt-60	NP_001021158.1	egt	<253..464	CDD:223071	66/214 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910