Protein Alignment Ugt301D1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_609882.1
• Gene: Ugt301D1 / 35105
• FlyBaseID: FBgn0032684
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 154/557 - (27%)
• Similarity: 260/557 - (46%)
• Gaps: 70/557 - (12%)

  Fly     7 WKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENL 71
            ::.:.|:|| |.::.....::|.: |... ||||.:......|.::|:.|..:..|...|.|.
 Frog    12 YRVFALLFL-GRVQLIEAEKLLAI-PLDG-SHWLSMRILVESLGQRGNQVVVLAPHSNIHIHP-- 71

  Fly    72 TEIIISPSFDIPKHFPKENIFSMQFVSDFNNL-----------ELWWTIGLMT------TEHAFK 119
            :|..|..::.:|  :.|| :...|.|...|::           .::..|..:|      .:|...
 Frog    72 SENYILRTYPVP--YSKE-LLKEQMVKSANDVFTKRPLLDKITNMYQRITNVTGIVFSACQHLLH 133

  Fly   120 DPKVKKLIESKDDHYDLVIIEQFF----------H--EAFLMFGKRFNCPVVTIGTMGYADNIDH 172
            ..::.:  |.::..:|..:|:.||          |  ..:|::|  ..|.:..:.|.
 Frog   134 SKEIMQ--ELQESAFDAALIDPFFPCGMIVAEYLHLPSVYLLYG--LPCGIDRLATQ-------- 186

  Fly   173 AMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPL 237
               ..:|.|.:|.....:||.|:|.||..||.|...|..:...:|.|..| ||.::....:
 Frog   187 ---CPSPLSYVPRHFTGNTDHMSFPQRLKNALLWPVDTFLCNLLYSPYAQ-LASEFLHREM---- 243

  Fly   238 PNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNA-TYGVIYFS 301
             .:|.|....|:.|:......|.|||.||.::.|||.:....:.|..:.:..:::: .:|.:.||
 Frog   244 -TILQLYSQTSVWLMKTDFVFDYPRPLMPNMVFVGGINCVGEQHLNQEFEKLVNSSGEHGFVVFS 307

  Fly   302 MGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLF 366
            :||.|  :::|..|...|.:|...:.|:|.|::...:..:|..|..:.||:||||:||||..:.|
 Frog   308 LGSMV--SEIPMNKAMDIAEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQNDLLAHPKARAF 370

  Fly   367 ITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDP 431
            |||.|..|..|||...|||:.:||:|||..|..:....|...:|....:|.:||...:..:||:|
 Frog   371 ITHAGSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNP 435

  Fly   432 QYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGA 496
            .||.:...:|....|.||||||.|..|:|:::||:||.||:.....:...||..|||:|.||...
 Frog   436 VYKENIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIGFLLAVL 500

  Fly   497 FLAIWLPWR----MIRRVHKWWLKGESSNKLNEGKKR 529
            ..|:::..:    :.||..|     .:|.|..:.|.:
 Frog   501 LTALFISLKCCTFVFRRCFK-----RNSKKQRKSKSQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_609882.1	Glycosyltransferase_GTB-type	37..483	CDD:471961	133/475 (28%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	148/529 (28%)