DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt301D1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	516	Identity:	148/516 - (28%)
Similarity:	243/516 - (47%)	Gaps:	81/516 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SHWLWLEHFQNDLLRQGHHVTSVN-----NHPTKHPHENLTEIIISPSFDIPKHFPKENIFSMQF 96
            ||||.|.....:|..:||.::.:.     ..|...||.:        |.::|.....::.|...|
Zfish    62 SHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSPHYD--------SINVPFLLGGDDQFYHSF 118

  Fly    97 VSDFNNLEL-----WWTIGL-MTTEHAF----------------KDPKVKKLIESKDDHYDL--- 136
            :  |..|::     |....| |..:..|                |:|.:.|.|  |:.::|:
Zfish   119 I--FRQLQIRREQRWTRFKLDMELKEKFSEMHRKICEMVIHIVEKEPAIMKQI--KEANFDIMLT 179

  Fly   137 -------VIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRM 194
                   |::..:.|...:     ||......|...:|.       ..:|.|.:|..|...||.|
Zfish   180 DPANGGGVVLAHYLHLPLV-----FNVQWTVHGEAHFAI-------APSPPSYVPFPLSQLTDSM 232

  Fly   195 TFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSID 259
            :|.||.||...|.....:.|....|....|..:.|     ||..:..:|.:...:.|:.|....|
Zfish   233 SFPQRIYNVLFSAVRLFLYRRTVGPHYSALCNRLF-----GPGLDYFELFQAADIWLMRADFVFD 292

  Fly   260 LPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAF 323
            .|||:||.:|.:||.|....|.||.||::||.:: .:|||..|:|:.|  ..||.:....|:.||
Zfish   293 FPRPTMPNVIYIGGFHCSPAKALPKDLEDFLQSSGEHGVIVMSLGTLV--AQLPMDIADEIVAAF 355

  Fly   324 GQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCV 388
            .:|.|:|||::..|...::.:|.::..|:||||:|.||..::|::|||..|..|.||.|||::.:
Zfish   356 AELPQKVIWRYTGDRPANVGNNTLLVNWLPQNDLLGHPKTRVFVSHGGTNGVFEAIYHGVPIVGL 420

  Fly   389 PLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLD 453
            ||..||..|.:|...:|.|:.|..:.:..:.....::.::|||.|:.:..::|...:|.|:.|||
Zfish   421 PLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDALQEVLNDPSYRSNMQKLSSLHKDTPLKPLD 485

  Fly   454 EATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLA------IWLPWRMIR 508
            .|.||.|:::|||||.||::....:|.:.|..:||      |.||.      ::|.::::|
Zfish   486 SALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVDV------GVFLVSVLCFIVFLMFKIVR 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	140/483 (29%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	140/483 (29%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.860