Protein Alignment CG10283 and Ccdc50

DIOPT Version :9

• Sequence 1: NP_001163006.1
• Gene: CG10283 / 35102
• FlyBaseID: FBgn0032681
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_011244304.1
• Gene: Ccdc50 / 67501
• MGIID: 1914751
• Length: 480
• Species: Mus musculus
• Alignment Length: 625
• Identity: 127/625 - (20%)
• Similarity: 201/625 - (32%)
• Gaps: 241/625 - (38%)

  Fly    23 VNEVCKEWLVREDGALAYKLQSQEINDFYKGNRYRNAVVREDFPTA---LHEQIKEKEQAQRRVD 84
            |.|||:::.|.||..||:.||.|||......|..||.:|:.|...|   ..|.:|.:.|.|:|..
Mouse    14 VKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYK 78

  Fly    85 AYRRRLTEQEEHDKRVAKEIADKL-----ERDLQEQQQKELMQSELIAKQMQEIYVNLPPVPPPV 144
            |.       |:||..:|:||.:||     .|.:||::.::      ||:.:||
Mouse    79 AL-------EQHDCEIAQEIQEKLTIEAERRRIQEKKDED------IARLLQE------------ 118

  Fly   145 TRDKSRPPPRPAKASIHLQQQQQTQQTQSTQQQHQPE---PSTSQQARYHSQLQQQQQQPLQLQQ 206
                                  :..|.:..:::|.||   .|......||....|.:
Mouse   119 ----------------------KELQEEKRRKKHTPEFSGGSVFGDNYYHEDGDQSR-------- 153

  Fly   207 QHFSQTDNYVGLSLIPNIVDLPGATAAC-------TTPSRNAQAHNQLLVSDVLPSPQQQQQQHH 264
               |:.|..:|          .|.:..|       |...:....|.|..:.|:        ::||
Mouse   154 ---SRRDRELG----------SGHSKFCRLQNDGKTVRQKEKPRHQQKNLEDL--------EEHH 197

  Fly   265 SRFHH------------AQQPPQQQQHQSSSPARRARAPTNAITSATTNMPSTSSITQHPPTHTE 317
            .....            ||...:||:.:.|...|..::|...|..
Mouse   198 PSERSLPSASWGRGRDGAQTACEQQERKRSGQERLWKSPLPKIRG-------------------- 242

  Fly   318 HPADIDELVDYADVADSIRDYNIAATSATATSASVVDAAATSLQKQRSPSHENLL---------- 372
                  |:....|..|...|::....|....|......:..|.||...|..|.:.
Mouse   243 ------EVFLSIDSEDWEADWSSGTRSPEKQSHHHGRLSPKSSQKTGLPCKEIVYGRDLGQGDHR 301

  Fly   373 --RTEPKFQKLSPEKYDQLVGNFGLGSVSGLGSGSVSGSGSGSAKAAERHMQQHADDIELYVDPC 435
              |..|:....|.:|      ......|:|:....:..:.|..|:|:.|       |.|.|
Mouse   302 ERRHRPRTSPFSEDK------ELRHHHVAGMKPRGIKEAVSTPARASHR-------DQEWY---- 349

  Fly   436 DYASLREIGLPLEEIQEISKKMKQEQKDELLARRLQAIESKDCVRQEHRDRLLAIEAQDKELAKM 500
                          ..||::|:   |::||||              .|.|...|..|||:|:|::
Mouse   350 --------------DAEIARKL---QEEELLA--------------THVDMRAAQVAQDEEIARL 383

  Fly   501 LQDRMNSKKLFSCRYNYLGFRKEKAKAKRAKEKARLRKTQQKEAAEAANGNGNLLCGTNSHCGPL 565
            |                  ..:||...|:|||:.:....::|.
Mouse   384 L------------------MAEEKKAYKKAKEREKSSLDKRKH---------------------- 408

  Fly   566 LPLPPDC-LSSNANQSQADIDVEAYSNPIDVLNSSREQRP 604
               .|:| |.:.:..|::....||:.:.||     |..||
Mouse   409 ---DPECKLKAKSAHSKSKEGDEAHRSKID-----RPSRP 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10283	NP_001163006.1	RILP-like	14..132	CDD:304877	39/116 (34%)
		HTH_MerR-SF	<440..497	CDD:295384	14/56 (25%)
Ccdc50	XP_011244304.1	CCDC50_N	4..128	CDD:373722	42/160 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850826
Domainoid	1	1.000	61	1.000	Domainoid score	I10454
eggNOG	1	0.900	-	-		E1_2B49I
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005601
OrthoInspector	1	1.000	-	-		oto94961
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4987
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830