Protein Alignment CG10283 and CCDC50

DIOPT Version :10

• Sequence 1: NP_001163006.1
• Gene: CG10283 / 35102
• FlyBaseID: FBgn0032681
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_848018.1
• Gene: CCDC50 / 152137
• HGNCID: 18111
• Length: 482
• Species: Homo sapiens
• Alignment Length: 747
• Identity: 137/747 - (18%)
• Similarity: 219/747 - (29%)
• Gaps: 356/747 - (47%)

  Fly    23 VNEVCKEWLVREDGALAYKLQSQEINDFYKGNRYRNAVVREDFPTALHEQIKE---KEQAQRRVD 84
            |.|||:::.|.||..||:.||.|||......|..||.:|:.|...|  :|::|   |.|||
Human    14 VKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVA--KQLQEEDLKAQAQ---- 72

  Fly    85 AYRRRLTEQEEHDKRVAKEIADKL-----ERDLQEQ---------QQKELMQSELIAKQMQEIYV 135
             .::|..:.|:.|..:|:||.:||     .|.:||:         |:|||.:.:...|...|.
Human    73 -LQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEF-- 134

  Fly   136 NLPPVPPPVTR---------DKSRPPPRPAK-------ASIHLQQQQQTQQTQSTQQQH------ 178
                   |.||         |..:|..|.|:       ....||:..:|.:.:..:.:|
Human   135 -------PATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLE 192

  Fly   179 QPE----------PSTSQQARYHSQLQQQQQQPLQLQQQHFSQTDNYVGLSLIPNIVDLPGATAA 233
            :||          .|:|.:.|.:..:..:|.:..:..|:...:       .|:|.|......:..
Human   193 EPEQHCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRR-------PLLPTISGEVFLSTE 250

  Fly   234 C---------TTPSRNAQAHNQ------------LLVSDVLPSPQQQQQQHHSRFHHAQQPP--- 274
            |         .|.:...|:.:|            |...:|:......|.:|..|.|..:.||
Human   251 CDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVVYGRDHGQGEHRKRRHRPRTPPFSE 315

  Fly   275 -QQQQHQSSSPARRARAPTNAITSATTNMPSTSSITQHPPTHTEHPADIDELVDYADVADSIRDY 338
             ::|.|...: ..:.|....|:::               |:...|                 ||
Human   316 SEEQLHLHDA-GMKPRVMKEAVST---------------PSRMAH-----------------RD- 346

  Fly   339 NIAATSATATSASVVDAAATSLQKQRSPSHENLLRTEPKFQKLSPEKYDQLVGNFGLGSVSGLGS 403
                                                        .|.||
Human   347 --------------------------------------------QEWYD---------------- 351

  Fly   404 GSVSGSGSGSAKAAERHMQQHADDIELYVDPCDYASLREIGLPLEEIQEISKKMKQEQKDELLAR 468
                                                           .||::|:   |::||||.
Human   352 -----------------------------------------------AEIARKL---QEEELLAT 366

  Fly   469 RLQAIESKDCVRQEHRDRLLAIEAQDKELAKMLQDRMNSKKLFSCRYNYLGFRKEKAKAKRAKEK 533
            ::              |...|..|||:|:|::|                  ..:||...|:|||:
Human   367 QV--------------DMRAAQVAQDEEIARLL------------------MAEEKKAYKKAKER 399

  Fly   534 ARLRKTQQKEAAEAANGNGNLLCGTNSHCGPLLPLPPDCLSSNANQSQADIDVEAYSNPIDVLNS 598
            .:....::|:..|..                    |....::|:...::|
Human   400 EKSSLDKRKQDPEWK--------------------PKTAKAANSKSKESD--------------- 429

  Fly   599 SREQRPHNGPLTNGSLTRDGGSGSNHSSMQRQQRNMVPIR--GEDDIYTLPVDSCRPGPRPLSLH 661
                .||                  ||..:|..|...||.  |||..||               |
Human   430 ----EPH------------------HSKNERPARPPPPIMTDGEDADYT---------------H 457

  Fly   662 VTEAMQPVQNNNSMTRSEHYGSEAGSHDSSHH 693
            .|       |..|.||  |:.....||...|:
Human   458 FT-------NQQSSTR--HFSKSESSHKGFHY 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10283	NP_001163006.1	CCDC50_N	14..132	CDD:464621	42/125 (34%)
		HTH_MerR-SF	<440..497	CDD:470628	13/56 (23%)
CCDC50	NP_848018.1	CCDC50_N	4..128	CDD:464621	41/120 (34%)