DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bsf and LOJ

DIOPT Version :9

Sequence 1:	NP_523596.2	Gene:	bsf / 35100	FlyBaseID:	FBgn0284256	Length:	1412	Species:	Drosophila melanogaster
Sequence 2:	NP_181456.1	Gene:	LOJ / 818508	AraportID:	AT2G39230	Length:	867	Species:	Arabidopsis thaliana

Alignment Length:	625	Identity:	117/625 - (18%)
Similarity:	221/625 - (35%)	Gaps:	168/625 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FAGFTRNVLVNSVREN--ETSNLLNNAPCMCGQFQNGFATNAAAKAELSLDKQIRRLDQDVRRIG 76
            |..:..|||.:.||.|  :.:..:.|...:.|...:...|....:|.|    :.|:.::.|:...
plant   203 FVPYVNNVLSSLVRSNLIDEAKEIYNKMVLIGVAGDNVTTQLLMRASL----RERKPEEAVKIFR 263

  Fly    77 RISRR--------------------DLEEVLDEIRSHRTATSSQSLLVIRCCGNL-VP---EELP 117
            |:..|                    ||...||.:|..|              |.| ||   |...
plant   264 RVMSRGAEPDGLLFSLAVQAACKTPDLVMALDLLREMR--------------GKLGVPASQETYT 314

  Fly   118 EVRTALVQE--------IWKTLNALNVPMDISHYNALLRVYLE-NEHGFAPTDFLAEIEAKGIEP 173
            .|..|.|:|        :...:....:||.:....:|:..|.: ||.|.| .|....:|.:|:.|
plant   315 SVIVAFVKEGNMEEAVRVMDEMVGFGIPMSVIAATSLVNGYCKGNELGKA-LDLFNRMEEEGLAP 378

  Fly   174 NRVTY------------------------------------------------------------ 178
            ::|.:
plant   379 DKVMFSVMVEWFCKNMEMEKAIEFYMRMKSVRIAPSSVLVHTMIQGCLKAESPEAALEIFNDSFE 443

  Fly   179 ---------QRLIARYCQQGDIEGATRILEFMRAKSLPVNENVFNSLILGHSQANDLESAKGILG 234
                     .::...:|:||.::.||..|:.|..|.:..|...:|:::|.|.:..:::.|:.|..
plant   444 SWIAHGFMCNKIFLLFCKQGKVDAATSFLKMMEQKGIEPNVVFYNNMMLAHCRMKNMDLARSIFS 508

  Fly   235 VMMQAGLEPSADTYTTLLCAFARHGDLAAVKETLAECEQKEIILLDKDLLDIVYTLTVNG----- 294
            .|::.||||:..||:.|:..|.::.|.....:.:.:......     :..:::|...:||
plant   509 EMLEKGLEPNNFTYSILIDGFFKNKDEQNAWDVINQMNASNF-----EANEVIYNTIINGLCKVG 568

  Fly   295 ----NGEHVDDVLTKLRLS---PGFNQDAVNVILRLVNKGHEDVGLKLLRVMPRSSRVNGEPVDV 352
                ..|.:.:::.:.|.|   ..:|    ::|...|..|..|..::..|.|..    ||:..:|
plant   569 QTSKAKEMLQNLIKEKRYSMSCTSYN----SIIDGFVKVGDTDSAVETYREMSE----NGKSPNV 625

  Fly   353 GAF--FIRQMVKANRPVEKILSICKSLQSEGLNPKALTIATEAGLTNGV-----INNALPLLQEM 410
            ..|  .|....|:|| ::..|.:...::|..|.   |.:.....|.:|.     :..|..|..|:
plant   626 VTFTSLINGFCKSNR-MDLALEMTHEMKSMELK---LDLPAYGALIDGFCKKNDMKTAYTLFSEL 686

  Fly   411 KNAGLPIRQHYFWPLICS----AESNQVLEIVRRMQQEFSVFPNSETVRDYVIPNLKEKN---WE 468
            ...||......:..||..    .:.:..:::.::|..: .:..:..|....:...||:.|   ..
plant   687 PELGLMPNVSVYNSLISGFRNLGKMDAAIDLYKKMVND-GISCDLFTYTTMIDGLLKDGNINLAS 750

  Fly   469 RIVTSLRDAG-VPNSTAVTSAVYSALVTHQIAEAAKIMEK 507
            .:.:.|.|.| ||:.......|.......|..:|:|::|:
plant   751 DLYSELLDLGIVPDEILHMVLVNGLSKKGQFLKASKMLEE 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsf	NP_523596.2	PPR_2	139..187	CDD:289786	11/117 (9%)
		PPR repeat	142..169	CDD:276811	8/27 (30%)
		PPR_1	169..202	CDD:289614	9/101 (9%)
		PPR_2	173..222	CDD:289786	14/117 (12%)
		PPR repeat	177..204	CDD:276811	7/95 (7%)
		PPR repeat	210..239	CDD:276811	6/28 (21%)
		PPR_2	213..257	CDD:289786	14/43 (33%)
		PPR repeat	245..274	CDD:276811	5/28 (18%)
		Pterin_binding	<456..>543	CDD:294150	13/56 (23%)
		PPR repeat	681..704	CDD:276811
		PPR repeat	710..739	CDD:276811
		PPR repeat	780..818	CDD:276811
		PPR repeat	825..854	CDD:276811
LOJ	NP_181456.1	PPR	170..202	CDD:273253
		PPR repeat	171..198	CDD:276811
		PPR_2	208..248	CDD:289786	9/39 (23%)
		PPR repeat	208..233	CDD:276811	7/24 (29%)
		PPR repeat	239..268	CDD:276811	6/32 (19%)
		PPR_2	312..357	CDD:289786	8/44 (18%)
		PPR	312..341	CDD:279828	4/28 (14%)
		PPR repeat	312..339	CDD:276811	4/26 (15%)
		PPR_2	344..392	CDD:289786	11/48 (23%)
		PPR repeat	345..374	CDD:276811	8/29 (28%)
		PPR	349..379	CDD:273253	9/30 (30%)
		PPR_2	378..427	CDD:289786	2/48 (4%)
		PPR repeat	380..408	CDD:276811	1/27 (4%)
		PPR	381..415	CDD:273253	1/33 (3%)
		PPR repeat	415..440	CDD:276811	0/24 (0%)
		PPR	450..484	CDD:273253	8/33 (24%)
		PPR repeat	451..478	CDD:276811	7/26 (27%)
		PPR_2	452..496	CDD:289786	12/43 (28%)
		PPR_2	482..531	CDD:289786	15/48 (31%)
		PPR repeat	486..513	CDD:276811	6/26 (23%)
		PPR	487..518	CDD:273253	9/30 (30%)
		PPR_1	513..545	CDD:289614	9/31 (29%)
		PPR repeat	519..548	CDD:276811	5/28 (18%)
		PPR_1	549..577	CDD:289614	4/32 (13%)
		PPR repeat	556..584	CDD:276811	4/27 (15%)
		PPR_2	592..637	CDD:289786	12/52 (23%)
		PPR	592..625	CDD:273253	9/40 (23%)
		PPR repeat	592..619	CDD:276811	7/34 (21%)
		PPR_1	619..652	CDD:289614	9/33 (27%)
		PPR_2	623..672	CDD:289786	12/52 (23%)
		PPR repeat	627..654	CDD:276811	6/27 (22%)
		PPR repeat	660..689	CDD:276811	5/28 (18%)
		PPR_2	693..742	CDD:289786	4/49 (8%)
		PPR repeat	695..724	CDD:276811	3/28 (11%)
		PPR	697..729	CDD:273253	3/32 (9%)
		PPR_2	729..777	CDD:289786	10/47 (21%)
		PPR repeat	730..758	CDD:276811	5/27 (19%)
		PPR	731..765	CDD:273253	9/33 (27%)
		PPR repeat	765..794	CDD:276811	5/26 (19%)
		PPR_1	794..826	CDD:289614
		PPR_2	798..844	CDD:289786
		PPR repeat	800..829	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2075
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050