Protein Alignment CG5790 and Cdc7

DIOPT Version :10

• Sequence 1: NP_609876.2
• Gene: CG5790 / 35095
• FlyBaseID: FBgn0032677
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_001689304.2
• Gene: Cdc7 / 5667636
• VectorBaseID: AGAMI1_007403
• Length: 524
• Species: Anopheles gambiae
• Alignment Length: 564
• Identity: 199/564 - (35%)
• Similarity: 271/564 - (48%)
• Gaps: 124/564 - (21%)

  Fly   107 QNANKELSTIQAKD------MQSVDKNEEALKELQESIPEINKIFD---VHCRIGSGTFSTVLLG 162
            |...::.:|:.|:|      :||...|..::.....|..|...::|   ||..|..||||||.|.
Mosquito    16 QEGAQQQTTVDAEDAGTPNELQSGGCNATSIAAADVSQREKLTVWDRYVVHGMIDKGTFSTVSLA 80

  Fly   163 TLQRERGLVETQRRRFAIKHHNPTNHPERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPY 227
            ||:.|:.|....||:||||...||:||.||.||:.||.:|||..||:|:....|:..:|..:|.|
Mosquito    81 TLRSEQHLPVGARRQFAIKLITPTSHPTRIAREILCMRKIGGQRNVVGLVDGFRHQGSVGLVMNY 145

  Fly   228 MTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNVIHRDVKPSNILYN-RRTGKFLLCDFGLA 291
            :..:.||..|..|...|::.|||.|||||..||...||||||||||.|:: |..|.::|.|||||
Mosquito   146 IPQEPFHQYYAQLTPAEVQRYLRQLLIALERVHLHGVIHRDVKPSNFLHSPRHGGTYVLVDFGLA 210

  Fly   292 QRIADDGSVVQSSDLSSREVFSILRDLENGRSVTLTDGNSAQAEAEDYMARRRMRALGGGGSVER 356
            |. .|.|            |.|:       |:.......:|.|:.|    :.:.:..|....|.:
Mosquito   211 QE-TDQG------------VLSL-------RAPDPCPETAAPAKCE----QEKPKQTGPVVPVRK 251

  Fly   357 AVTGPPSI-QKLREQAGGHLTKKDVANQR-ADTMR--------------LLNRLRLVSPNADPNN 405
            |:..|..: .......||..::.:.:..| .|..|              :.||. ||.|
Mosquito   252 ALKRPLKLSNSTTNDLGGVPSRPNSSGGRTTDASRPPPPSACSCYGRAQVCNRC-LVRP------ 309

  Fly   406 YVVSTNTSKKEMHASRAGTPGYRPPEVLLRYPKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCG 470
                      ||:|.||||||||||||||:||.|:||||:||||||.|.|||.|:|||....|..
Mosquito   310 ----------EMNAPRAGTPGYRPPEVLLKYPHQTTAVDIWAAGVIFLGLLSKLYPFFGNVDDLT 364

  Fly   471 ALAEIINLFGDMPVRKTAFLLDR-----LILLAQKVNTLDLRRVCMRFR--HADFFLAPEIQRKY 528
            :||.:|.:||...:|:||..|||     .:.:|::  ...|||:|..||  |            |
Mosquito   365 SLAHMIEVFGYERMRETARALDRTLHCDAVTMAKR--PYSLRRLCQNFRAIH------------Y 415

  Fly   529 QR----------------------PDGTTEM----CRSCEQPTFNCLC-------SNSGHNLERY 560
            .|                      |.|..|.    |.:|.:|...|||       :::|.:....
Mosquito   416 GRELGSGAGGGDAGGVAVAGGSSPPSGRDEEQRYGCDNCCKPPDTCLCQRRRAVGASAGDDEAEP 480

  Fly   561 DG---LDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFFSDQH 601
            .|   .|.:...||:||.||||.||.:||:|.|||:||:|..|:
Mosquito   481 VGDTDCDEYGPDAYELLERLLETNPHRRISATEALQHPYFQVQY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5790	NP_609876.2	STKc_Cdc7	143..597	CDD:270921	188/516 (36%)
		Protein Kinases, catalytic domain	<238..>363	CDD:473864	44/125 (35%)
		Protein Kinases, catalytic domain	<427..597	CDD:473864	81/212 (38%)
Cdc7	XP_001689304.2	None