DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5790 and CG12147

DIOPT Version :9

Sequence 1:	NP_001286037.1	Gene:	CG5790 / 35095	FlyBaseID:	FBgn0032677	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	NP_649536.1	Gene:	CG12147 / 40651	FlyBaseID:	FBgn0037325	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	69/282 - (24%)
Similarity:	111/282 - (39%)	Gaps:	75/282 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 KNEEALKELQESIPEI---NKIFDVHCRIGSGTFSTVLLGTLQRERGLVETQRRRFAIKHHNPT- 186
            :.:....|.::|:|||   .| :.:..|||:|:|     |.|.:..||  ....:.|||..:.|
  Fly    47 RQDRRFSEEKQSLPEIIVAGK-YRLLKRIGNGSF-----GELFQAEGL--KYHEKVAIKLESSTV 103

  Fly   187 NHPERILRELECMYRIGGV-ENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLR 250
            .|| .:.||.    ||.|: :..:||          ..:..|.|...::.:...|..|.:.|.|.
  Fly   104 KHP-LLPREA----RIYGILQGGLGI----------PHVKHYATEGAYNVMVMDLLGPTLEDLLN 153

  Fly   251 ----------------NLLIALRHVHKFNVIHRDVKPSNIL--YNRRTGKFLLCDFGLAQ----- 292
                            .:|..:..:|:...||||:||.|.|  .||...:..:.|||||:
  Fly   154 LCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKPDNFLMGLNRHQTQVYMIDFGLAKKFYSL 218

  Fly   293 RIADDGSVVQSSDLSSREVFSILR----------DLENGRSVTL--------TDGNSAQAEAE-- 337
            |........::.||.....::.:|          |||:...:.|        ..|..||::|:
  Fly   219 RTQKHIGYTENRDLVGTARYASVRAHYAEQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKY 283

  Fly   338 ----DYMARRRMRALGGGGSVE 355
                :|.|...::.|..|..||
  Fly   284 EKIAEYKANIPLQQLCSGLPVE 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5790	NP_001286037.1	STKc_Cdc7	143..597	CDD:270921	64/262 (24%)
		S_TKc	145..597	CDD:214567	63/260 (24%)
		PKc_like	<238..>363	CDD:304357	39/165 (24%)
		PKc_like	<364..>462	CDD:304357
		PKc_like	<427..597	CDD:304357
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	64/262 (24%)
CG12147	NP_649536.1	SPS1	67..>306	CDD:223589	64/262 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452722
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030